NMJ Blockers Flashcards

1
Q

Structure of NMJ blockers

A

Analogs of Ach

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2
Q

What are the NMJ blockers

A

Tubocurarine

Succinylcholine

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3
Q

Which NMJ blocker is non-depolarizing

A

Tubucurarine

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4
Q

Which NMJ blocker is depolarizing

A

Succinylcholine

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5
Q

What receptor do NMJ blockers bind

A

Nm

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6
Q

What kind of paralysis do NMJ blockers cause

A

Flaccid

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7
Q

What is Tubocurarine used for

A

Anesthesia

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8
Q

What is Succinylcholine used for

A

ET tubation

ECT

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9
Q

What counteracts Tubocurarine

A

Neostigmine

Edrophonium

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10
Q

Mode of administration of Tubocurarine

A

IV

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11
Q

Mode of administration of Succinylcholine

A

IV

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12
Q

Which NMJ blocker may bind M receptors and cause histamine release

A

Tubocurarine

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13
Q

Which NMJ blocker may cause malignant hyperthermia

A

Succinylcholine, when combined with halogenated anesthetic

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14
Q

Tx for malignant hyperthermia

A

Dantrolene

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15
Q

Does tubocurarine cross the BBB

A

No

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16
Q

How would you describe the duration of succinylcholine activity

A

Fast - Onset, duration