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Pharm Midterm 1 > Beta Antagonists > Flashcards

Beta Antagonists Flashcards

1
Q

What is the prototype beta blocker

A

Propranolol

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2
Q

MAJOR AE of Propranolol

A

Bronchoconstriction

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3
Q

Contraindication of Propranolol

A

COPD
Asthma
Variant Angina

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4
Q

Beta 1 and 2 blocker

A

Propranolol
Nadolol
Timolol

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5
Q

Beta 1 selective blocker

A

Atenolol
Metoprolol
Esmolol

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6
Q

CVS effect of Propranolol

A

Decrease HR, contractility

Increase TPR

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7
Q

Metabolic effect of Propranolol

A

Decrease glycogenolysis, glucagon secretion

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8
Q

DOC for performance anxiety/stage fright

A

Propranolol

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9
Q

Uses of Propranolol

A 
HTN
Migraine
Hyperthyroidism
Chronic angina
A-fib, MI
Essential tremor
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10
Q

Effects of prolongued hypoglycemia in diabetics

A

Syncope

Tachycardia

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11
Q

Difference between Nadolol and Propranolol

A

Longer duration (angina and HTN)

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12
Q

Effect of Propranolol on fat

A

Decrease HDL

Increase LDL and TAGs (block HSL)

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13
Q

What kind of beta blockers can improve lipid profile

A

Beta 1 selective

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14
Q

What can happen with abrupt withdrawal of Propranolol

A

HTN

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15
Q

What is Timolol used for

A

HTN
Migraine prophylaxis
Open angle glaucoma

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16
Q

When do you give Atenolol or Metoprolol

A

HTN with impaired pulm or IDDM

17
Q

What do you use for long term angina management

A

Atenolol
Metoprolol
Nadolol

18
Q

What reduces mortality post-MI

A

Atenolol

Metoprolol

19
Q

What is good for controlling arrhythmia (supraventricular or thyrotoxicosis)

A

Esmolol

20
Q

Which beta blocker is safer in critically ill pts

A

Esmolol

21
Q

What do you use for preop HTN and in acutely ill MI pts and why

A

Esmolol
t1/2 = 10min
IV admin

Pharm Midterm 1 (36 decks)

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