Beta Antagonists Flashcards
What is the prototype beta blocker
Propranolol
MAJOR AE of Propranolol
Bronchoconstriction
Contraindication of Propranolol
COPD
Asthma
Variant Angina
Beta 1 and 2 blocker
Propranolol
Nadolol
Timolol
Beta 1 selective blocker
Atenolol
Metoprolol
Esmolol
CVS effect of Propranolol
Decrease HR, contractility
Increase TPR
Metabolic effect of Propranolol
Decrease glycogenolysis, glucagon secretion
DOC for performance anxiety/stage fright
Propranolol
Uses of Propranolol
HTN Migraine Hyperthyroidism Chronic angina A-fib, MI Essential tremor
Effects of prolongued hypoglycemia in diabetics
Syncope
Tachycardia
Difference between Nadolol and Propranolol
Longer duration (angina and HTN)
Effect of Propranolol on fat
Decrease HDL
Increase LDL and TAGs (block HSL)
What kind of beta blockers can improve lipid profile
Beta 1 selective
What can happen with abrupt withdrawal of Propranolol
HTN
What is Timolol used for
HTN
Migraine prophylaxis
Open angle glaucoma
When do you give Atenolol or Metoprolol
HTN with impaired pulm or IDDM
What do you use for long term angina management
Atenolol
Metoprolol
Nadolol
What reduces mortality post-MI
Atenolol
Metoprolol
What is good for controlling arrhythmia (supraventricular or thyrotoxicosis)
Esmolol
Which beta blocker is safer in critically ill pts
Esmolol
What do you use for preop HTN and in acutely ill MI pts and why
Esmolol
t1/2 = 10min
IV admin
