Presynaptic Cholinergic Antagonists Flashcards

1
Q

What are the Presynaptic Cholinergic Antagonists

A

Hemicholinium
Vesamicol
Botulinum Toxin

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2
Q

What blocks choline transporter (CH1)

A

Hemicholinium

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3
Q

What blocks vesicular Ach-H+ antiporter (VAChT)

A

Vesamicol

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4
Q

What blocks synaptic vesicle fusion

A

Botulinum

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5
Q

Which are used for research

A

Hemicholinium

Vesamicol

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6
Q

ROA for Botulinum

A

Injection

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7
Q

When do you use botulinum

A

Blepharospasm (excess muscle tone)
Wrinkles
HA and Pain

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8
Q

What does blocking CH1 do

A

Stop uptake and synthesis of Ach

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9
Q

What does blocking VAChT do

A

Prevent Ach storage

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10
Q

What does blocking synaptic vesicle fusion do

A

Prevent Ach release

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