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Pharm Midterm 1 > Eicosanoids > Flashcards

Eicosanoids Flashcards

1
Q

What are the eicosanoids

A 
Dinoprostone
Carboprost tromethamine
Misoprostol
Alprostadil
Epoprostenol
Latanoprost
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2
Q

What are the eicosanoid antagonists

A

Zileuton
Zafirlukast
Montelukast

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3
Q

PGE2 analog

A

Dinoprostone

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4
Q

15-methyl-PGF2 alpha analog

A

Carboprost Tromethamine

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5
Q

PGE1 derivative

A

Misoprostol

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6
Q

PGE1 analog

A

Alprostadil

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7
Q

Is a prostacyclin (PGI2)

A

Epoprostenol

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8
Q

PGF2 alpha derivative

A

Latanoprost

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9
Q

Maintains patency of the Ductus Arteriosus

A

Alprostadil

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10
Q

Used in severe pulm HTN

A

Epoprostenol

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11
Q

Function of eicosanoids

A 
SM contraction (Ca)
cAMP relaxation
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12
Q

Cervical ripening at term

A

Dinoprostone

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13
Q

Induce abortion

A

Dinoprostone
Carboprost Tromethamine
Misoprostol

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14
Q

Prevent PUD in chronic NSAID use

A

Misoprostol

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15
Q

Used in impotence

A

Alprostadil

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16
Q

Prevents platelet aggregation on dialysis

A

Epoprostenol

17
Q

Gold standard for glaucoma

A

Latanoprost

18
Q

LOX inhibitor

19
Q

Inhibit LTD4 binding

A

Zafirlukast

Montelukast

20
Q

What do glucocorticoids inhibit

21
Q

How do NSAIDS decrease PGs

A

Inhibit COX 1 and 2

Pharm Midterm 1 (36 decks)

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