Sepsis Flashcards

1
Q

def. sepsis

A

disfunción orgánica por una respuesta no regulada secundaria a un proceso infeccioso

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2
Q

lugar en mortalidad

A

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3
Q

Identificación y tx oportuno disminuye mortalidad y morbilidad

A

50%

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4
Q

riesgo de mortalidad por sepsis

A

4-50%

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5
Q

SRIS criterios (4)

A

distermia
taquipnea
taquicardia o bradicardia
alteración de la cuenta blanca

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6
Q

choque séptico
definición
criterios

A
choque séptico
definición: disfunción CV + sepsis
criterios
>2 acido láctico, acidosis metabólica
3ºC periférica vs. central 
retraso llenado capilar, oliguria
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7
Q

respuesta inflamatoria

A

antiinflamatoria

pro-inflamatoria

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8
Q

% comorbilidad

A

50

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9
Q

comorbilidad <1 año

A

prematuro, cardiopatías congénitas, neumopatía crónica

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10
Q

comorbilidad 1-6 años

A

neuromuscular

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11
Q

comorbilidad 9 años

A

neoplasias

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12
Q

QUICK SOFA

A

CV: hipotensión
FR: taquipnea
Neuromuscular: Glasgow

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13
Q

Manejo

A

1º hipotensión –> sol salina .9% bolo 20 ml/kg
drogas vasoactivas: adrenalina
ATB

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14
Q

Pasos surviving sepsis (4)

A

1) cultivo
2) ATB amplio espectro
3) de - escalación
4) identificar y controlar la fuente de infección

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15
Q

Biomarcador S y E?

A

no existe BIOMARCADOR s y e para dx y pronóstico

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16
Q

Tx específico basado en?

A

genómica, transcriptómica, proteómica