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CNS > sensory systems and pain physiology > Flashcards

sensory systems and pain physiology Flashcards

1
Q

what to pancilan corpuse respond to

A

deep pressure

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2
Q

what do ruffini corpuscles respond to

A

warmth

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3
Q

what do meissener copurs respond to

A

light touch

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4
Q

what do merkels corpus respond to

A

touch

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5
Q

funciton of free nerve endings

A

pain

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6
Q

what signifies the intesity of a stimuls

A

frequency of action potential

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7
Q

how to determine where a stimulous is from

A

receptive feild

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8
Q

what is the trigger zone

A

area wher a transution sings turns into action poteials

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9
Q

what is a recepive feild

A

area of stimuls that is applied, it is area where it connects to other protcepotrs

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10
Q

what are hte types of cutanoes sensoation fibers

A

ab, Aδ an C

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11
Q

what is ab

A

large myelatied

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12
Q

spped of ab

A

30 -70m/s

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13
Q

what does ab meausre

A

touch, pressure and vibration

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14
Q

what is Aδ

A

small myelatied

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15
Q

speed of Aδ

A

5 - 30m/s

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16
Q

what does Aδ meause

A

fast paina nd pressure

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17
Q

what is c fibers

A

small unmeya.ted

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18
Q

spped of c fibers

A

0.5 - 2m/ s

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19
Q

funciton of c fibers

A

warth and slow pain

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20
Q

where to they enter the spinal cord

A

dorsla root ganglia

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21
Q

wher ot crial nerves enter spial cord

A

cral nerve ganglia

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22
Q

what are the mechano recpigve fibers

A

aa and ab

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23
Q

fibes for protecption

A

aa and ab

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24
Q

aa fiber

A

muscle spiner lfierb with fastes spped

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25
Q

where do mechang repite fiebrs synape

A

cunetate and gracile nulcie in the medulla

26
Q

which tract do mechanorepcoi go up

A

isilatarl dorsal columbs

27
Q

where do the mechanorective fibers cross

A

over the midline in the brain stem and to the restic formation and thalamus

28
Q

what type for fibesr are thermorecpive and nociepetie

A

Aδ and c

29
Q

where do thermo and noticerep fibers sysnape

A

dorsal horn

30
Q

what is the course of the thermocrepa nd notercpic fiebrs

A

cors midline of spinal cord after synaping in it
and go up later spinothalic tract to reticuar foramnat, thaalmau and cortex

31
Q

what is brown sequard synomde

A

where contralateal side loses pain and temparute
and ispilati side lose, viraion, motor funciton, deep touhg and proipoception

32
Q

where doe sthe termiation occur

A

somatosensory cortex of the post cental gyrus

33
Q

what is rapidly adapting cells

A

they change quickly to ignaor stimul, stopping seeing acitno potiona

34
Q

what are slowi adamping cells

A

they don’t sop seing aciton protional against a stimulus

35
Q

benifits of converges

A

reduces no. of nurions,

36
Q

downsides of convergence

A

reduces acuity

37
Q

what are speific asing pahtwyas

A

where there are sperate htings for things like touch and temparues

38
Q

non specfici ascening pathway

A

same pathway for both temperature and touch

39
Q

what is latarl inhibitoin

A

where one sensory inputs actiion cuase inhibtion of a neighbour

40
Q

what happesn to frequeyc of action potens in neihgt bof a latarl inhbing neruon

A

it drops below frequency , making it look like it si not there at all

41
Q

what are the types of pain

A

sharp, stabing difues , fast or slow, acute, chronci, viscer, refered , phantom limbpain

42
Q

how are signa transion of pain acitved in nociecptors

A

low ph or heat
local cemicla meidatiors

43
Q

examples of local cehmcial meidator in nociceptors

A

bradykinin, histamine, prostaglandins

44
Q

what are exampoles of low ph and heat sencors

A

asic and trpv

45
Q

how is asic funcitons

A

it opens an ion channel and releases soiudm into a cell to relaea an action potential

46
Q

what happens with activating periaqudaclt gray matter

A

it causes the inhition of pain though sending signal to the nucleus raplh

47
Q

how does the nuclus rahe mangus inhibt pain

A

reaslses serotoion which project down to the doral horne nuclear to block pain at that level

48
Q

what type of recprot is on the pag

A

opiod

49
Q

what type of fibers are need to activate inhibitor fibers of pag

A

aa/ ab

50
Q

gate contorl thearpy

A

block pain signsal of ad/ c fibers

51
Q

what do the nuclouer raphe relse

A

endoprones/ opoids pepistes

52
Q

whre do the opoid peptities travle down

A

doral spinothla colub

53
Q

how to nsaids work

A

inhibit cyclooxygenase stoping arachoni acids turnign to proslagins

54
Q

how to prostaglins work

A

they snesity nocipetor to bradykinins

55
Q

what are bradykinins

A

a peptise that cuases inflmatoatino
vasodialte
edmea
muscle contraction

56
Q

what typ eof pain if nsaids effective agianst

A

ones that cause infolaton

57
Q

how does lcoal anathic work

A

block na action potpan and thus all axonal tranaiotn

58
Q

how to morpones work

A

reudce senicve of nociapes, block transmait in doral horn through epidural transioant
activate desncing hinhigor pathawy

59
Q

what is cox1

A

for prosuicng gastic muous
help kindesy
produce platel

60
Q

what is cox 2

A

infmalton, pain fever and inhibit palteles

61
Q
A

CNS (36 decks)

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