Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CNS > MS > Flashcards

MS Flashcards

1
Q

what part of the spine does ms effect

A

white mater

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how does ms effect the spie

A

caues demylation and inflatom of the spine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

course of ms disesease

A

it is remitiing disease, ie gets worse then better gradually

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

how preveanlt is ms

A

1 in 300 people

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

where is ms found more

A

it is more prevalent the further north you go

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

which gender does ms mainly effect

A

females

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what viurs may ms be associated with

A

epstein barr viurs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

common problems in ms relapse

A

optic neurtisi - inflamtion of optic nerve
sensory smpons
brian stem - diplopia (double vision), vertiog
spinal cord – bilatler motor symptons#
bladder inovmvetn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

signs of optic enuritsi

A

vision loss
pain in movnig eye
colour vision impaired
resolves within weeks or months
swelling of the optic disc
cuaes pupill defect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is relative affernt pupillary defect

A

where wehn a tourch is shined on a pupil it will cause it not to constrict due to damage to optic nerve, when shine on other pupil both pupils will constic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

which part of the brain is internuclear ophthalmoplegia associated with

A

pons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is sigs of internuclear ophthalmoplegia

A

diffucily moving both eyes horizonally at the same time
one eye will have nystagmus towards the lateral aspect and the other eye will not move

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

effect of spinal cord lesion in ms

A

cuase band of hyperaesthis or numbes in the area
can cause bladder or bowel problems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what type of cell is responsibel for demylination

A

activated t cells crossing the bbb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is required for an ms diagnosis

A

multople esposes of demaites, happening in differnt areas over a period of tiem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what hormone may be linked ot ms in women

A

oestrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what is a characties loss that shows progression of the disase

A

loss of the axons

18
Q

what is the progressive stage in ms

A

accumation and symtons such as furher fatique, pins and eends, stiffnes, balance and slurrend speahc, bladder probesl e.ct

19
Q

what to do in ms exam

A

pupillary defects
nystagusms or absomaly eye movements
cerebellar signs such as atraxia
weakness
spasticicyt
hyperreflexia
plantar extensor

20
Q

what are the type sof ms

A

relapsing / remitting 85%
seconary progressive
primary pregssid 10%

21
Q

what is primary progessve

A

where there is none of the relaping and remitting and it is just a deterning in ms, and cause spinal and vbldder problems
deteriatin is at a constant rate

22
Q

what is seconary progessive

A

there at first is erapinga nd remiting, then it has a general deteriating of ms that that does improve

23
Q

criteerai for mri ms diaganso

A

mcdonalds criteria

24
Q

clincial criterai for ms diagnossi

A

posers criteri - mianly 2 realpse in different area so cns months or years apart

25
Q

what should show in a lumar punctre for ms

A

normal csf glucose and protin
few whiet cells
ooligocloant band that are just in the csf but not the serum - indicates inflation of just the spinal cord and notwerhe else

26
Q

oligoclonat bands

A

indicate inflmaton inthe csf

27
Q

differneatl diagnos sof ms inchial

A

acute disseminated encephalomylitis - after viral ollenss

28
Q

differnetail diagnois of ms in adults

A

sarcoidosis
vasculitis
lyme disease
tb

29
Q

investiags for ms

A

lumbar punctues
blood test for autoantimary screen, virolgy, b12
chest x-ray to rule out tb and sarcoidosis

30
Q

treatemtent of acute relaspe in ms

A

oral prednisoloen - for 3 days with gastic protection

31
Q

what are treatement for spacity in ms

A

muslce realaxsi and antispasmotics

32
Q

treatment for dysaethesia

A

amitriptyline, gabapentin

33
Q

treatment for over active unary symosn

A

anticholineragic rx

34
Q

treatemt for underative urarl fuction

A

bladder stimualtion, seelf catheretiesation

35
Q

other problesm as a result of cs

A

depression
fatique
tremtors
viiosn - particuerl oscilliopisa
speech
motor and sernory impariemtn

36
Q

treatemtn for oscillopsia

A

carbamazepine

37
Q

fist line disease modify

A

oral - teriflunomide, dimethyl fumarate
sc/ im infeciton - beta interferons, glatiramer aceetaet

38
Q

second line disease modifiying

A

tablets - fingolimod/ ozanimod/ posenimod, cldridine
sc injections/ iv infusions - natalizumab, ocrelizumab, ofatumumab, alemtuzumub
stem cell treatemn

39
Q

main priiamry and seconary dmt for ms

A

primar - ms ocrelizumab
secondary - ms - siponimod

40
Q

can immouspueeoisn be usecd

A

yes

41
Q

downsie of immuo suppersion

A

has risk o prgessive multifocal leukoencephalopathy

42
Q
A

CNS (27 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions