Schizophrenia And It’s Causes Flashcards

1
Q

Schizophrenia MZ:DZ?

A

45:15%

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2
Q

Major histocompatibility complex on which chromosome?

A

6

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3
Q

Biological stress factor of schizophrenia?

A

Immune activation, premature birth, low birth weight, perinatal hypoxia, intrauterine infection, ante-partum bleeding

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4
Q

Hypofrontality causes?

A

Negative symptoms

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5
Q

Increased dopamine in nucleus accumbens causes?

A

Positive symptoms

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6
Q

Drugs causing schizophrenia?

A

Amphetamine ketamine, LSP, cannabis,cocaine, LDOPA

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7
Q

Organic psychosis?

A

Epilepsy, cerebral trauma, encephalitis, demyelination, neurodevelopmental disorders, endocrine disorders, drugs, toxins, dementia

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8
Q

Resistant cases of psychosis should be treated with?

A

Clozapine

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9
Q

Olanzapine causes?

A

Weight gain side effect due to binding at histamine receptors

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10
Q

Blocking alpha 1 receptor?

A

Postural hypotension

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11
Q

Blocking dopamine receptors?

A

Neuroleptic malignant syndrome
Hypotension arrhythmia
Parkinsonism symptoms
Raised prolactin

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12
Q

Atypical antipsychotics side effects

A

5HT2 receptors

Metabolic, raised prolactin, sedation, neutropenia with clozapine

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13
Q

Clozapine can cause?

A

Neutropaenia, also dribbling

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14
Q

Electroconvulsive treatment to treat?

A

Psychosis associated with depression, or with catatonia

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15
Q

Side effect of ECT?

A

Short term memory loss

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16
Q

CBT session number?

A

12-20

17
Q

CBT model contains?

A

Behaviour
Thoughts
Feelings

18
Q

Expressed emotion?

A

Critical comments and over involvement

19
Q

Key area affected in psychosis?

A

Striatum