Anxiety Drugs Flashcards
How to treat panic disorder?
Benzodiazepines
SSRI
CBT
What do SSRIs work well in?
OCD
GAD
PD
PTSD
What is a 5HT1A receptor agonist for GAD?
Buspirone
Drug that increases anxiety, benzodiazepine antagonist?
Flumazenil
OCD Is due to overactivation of which pathway?
Direct
What happens in OCD?
Caudate sends gabaergic inhibitory projections to GP, which sends inhibitory protections to thalamus which then projects to orbitofrontal cortex
Which drugs have a potential for abuse?
Benzos
Predictable stimulus pattern would be shown?
Temporal lobe
Unpredictable stimulus?
Shown in nucleus accumbens
What changes can amphetamine and cocaine bring about?
Hypofrontality
Increased activity of VTA tyrosine hydroxylase
CREB
GLUR1 AMPA
In a cocaine addict what happens?
D2 receptors decrease