Anxiety Drugs Flashcards

1
Q

How to treat panic disorder?

A

Benzodiazepines
SSRI
CBT

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2
Q

What do SSRIs work well in?

A

OCD
GAD
PD
PTSD

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3
Q

What is a 5HT1A receptor agonist for GAD?

A

Buspirone

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4
Q

Drug that increases anxiety, benzodiazepine antagonist?

A

Flumazenil

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5
Q

OCD Is due to overactivation of which pathway?

A

Direct

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6
Q

What happens in OCD?

A

Caudate sends gabaergic inhibitory projections to GP, which sends inhibitory protections to thalamus which then projects to orbitofrontal cortex

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7
Q

Which drugs have a potential for abuse?

A

Benzos

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8
Q

Predictable stimulus pattern would be shown?

A

Temporal lobe

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9
Q

Unpredictable stimulus?

A

Shown in nucleus accumbens

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10
Q

What changes can amphetamine and cocaine bring about?

A

Hypofrontality
Increased activity of VTA tyrosine hydroxylase
CREB
GLUR1 AMPA

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11
Q

In a cocaine addict what happens?

A

D2 receptors decrease

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