Rheumatology basics Flashcards
Arthropathy
disease of the joint
Arthritis
inflammation of the joint
Arthralgia
pain in a joint
What causes loss of regulation of antibody production?
multifactorial
- genetic predisposition
- environmental insults:
- infection and prolonged chemical exposure
what type of arthritis have autoantibodies involved?
seropositive
what are the seropositive arthritic conditions?
Rheumatoid Arthritis SLE Sjogren's Systemic sclerosis (limited) Systemic sclerosis (diffuse) Mixed Connective Tissue Disease All liver disease Small cell vasculitis Myositis Anti-phospholipid syndrome
what seropositive antibodies are involved in rheumatoid arthritis?
Anti-CCP
what seropositive antibodies are involved in SLE?
ANA Anti-dsDNA Anti-Sm Anti-Ro Anti-RNP
what seropositive antibodies are involved in Sjorgen’s?
ANA
Anti-Ro
Anti-La
what seropositive antibodies are involved in Systemic sclerosis (limited)?
ANA
Anti-centromere
what seropositive antibodies are involved in Systemic sclerosis (diffuse)?
ANA
Anti-Scl-70
what seropositive antibodies are involved in MCTD?
ANA
Anti-RNP
what seropositive antibodies are involved in all liver disease?
ANA
what seropositive antibodies are involved in small cell vasculitis?
ANCA
what seropositive antibodies are involved in myositis?
Anti-jo1