Large Cell Vasculitis Flashcards
1
Q
what is it?
A
primary vasculitis which causes granulomatous inflammation predominantly of aorta and its major branches
2
Q
what is the difference TA and GCA?
A
differ in age of onset, and GCA mainly occurs in temporal arteries
3
Q
how do they present?
A
early features are non-specific, low-grade fever, malaise, night sweats, weight loss, arthralgia, fatigue claudicant symptoms in upper and lower limbs if untreated - vascular stenosis and aneurysm can occur - reduced pulses - bruits
4
Q
how is it investigated?
A
CPR, PV/ESR elevated MR angiography: detect thickened vessel walls and stenosis
