Quiz 2 Part 2 : Neurophysiology Flashcards

1
Q

electrical activity of a cell

A

neurophysiology

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2
Q

two ways neurons communicate

A

electrical and chemical

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3
Q

within a neuron

A

electrical (neurophysiology)

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4
Q

between neurons

A

chemical (neurochemical)

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5
Q

outer layer of the neuron that is a lipid bilayer

A

cell membrane

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6
Q

separates neuron from what it floats in (CSF)

A

cell membrane

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7
Q

the inside of the cell is more _____ than the outside of the cell

A

negative

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8
Q

negatively charged ions

A

anions

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9
Q

positively charged ions

A

cations

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10
Q

ions are dissolved in …

A

intracellular fluid

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11
Q

what is the charge caused by

A

the difference in ions in the intracellular and extracellular space

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12
Q

membrane potential of -60 to -80mV

A

resting potential

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13
Q

when the cells interior has a negative polarity at rest

A

resting potential

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14
Q

proteins that span the cell membrane and allow different types of ions to pass

A

ion channels

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15
Q

channels that are open all the time

A

leak channels

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16
Q

allow only potassium ions to cross freely, restrict the flow of certain ions

A

selective permeability

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17
Q

forces that drive ion movement across the membrane

A

diffusion and electrostatic pressure

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18
Q

diffusion

A

molecules distribute themselves evenly through a liquid where they are dissolved

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19
Q

concentration gradient

A

ions move from areas of high concentration to areas of low concentration
social distancing for molecules

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20
Q

electrostatic pressure

A

causes ions to flow towards oppositely charged areas

  • opposites attract
  • like charges repel
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21
Q

typical ionic distribution at rest

A

salty banana

  • inside of cell has lots of K+
  • outside cell has ions that make up salt Na+ and Cl-
  • more Ca2+ outside cell than in
  • cover the banana in salt
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22
Q

how does K+ move in relation to diffusion

A

diffusion pushes it out of the cell

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23
Q

how does K+ move in relation to electrostatic P

A

pushes it back into the cell

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24
Q

negatively charged proteins (A-)

A

do not move, stuck inside the membrane always there

25
how does Cl- move in relation to diffusion
moves into the cell
26
how does Cl- move in relation to electrostatic P
pushes it outside of the cell
27
how does Na+ move in relation to diffusion
into the cell
28
how does Na+ move in relation to electrostatic P
into the cell, opposites attract
29
what ion contributes most to keeping neuron at resting potential
K+
30
at rest, why do K+ ions move into the negative interior
electrostatic pressure
31
when does K+ reach equilibrium?
when the movement out is balanced by the movement into the cell
32
why do neurons use a sodium potassium pump?
to maintain resting potential
33
sodium potassium pump
pumps 3 Na+ out of the cell and 2 K+ into the cell | allows ion exchange against concentration gradient
34
brief but large change in membrane potential that originates at the axon hillock
action potential
35
Patterns of action potentials carry information to ___
postsynaptic targets
36
at rest the membrane is __
polarized
37
decrease in membrane potential
depolarization
38
these increase membrane potential
repolarization and hyperpolarization
39
voltage change that spreads passively across membrane, diminishing as it moves away from the point of stimulation
local potentials
40
produces small local depolarization, pushes cell closer to threshold, makes it more likely an action potential will occur
Excitatory Postsynaptic Potential (EPSP)
41
produces small hyperpolarization | - pushes neuron farther away from threshold
Inhibitory Postsynaptic Potential (IPSP)
42
where does the integration between EPSPs and IPSPs
axon hillock
43
neuron fires at full amplitude or none
all or none phenomenon
44
increased frequency =
increased stimulus strength
45
does a louder noise mean there are larger action potentials?
no. it means there are multiple action potentials
46
resting membrane potential
-60 to -80 mV
47
what is/what happens at threshold?
threshold = -55 to -40 mV | the voltage gated Na+ channels open
48
what is/ what happens at the peak of the action potential? | what is this known as?
peak = +40 mV Na channels close, K channels open known as repolarization
49
what is hyperpolarization in mV
below -80mV
50
absolute refractory period
does not matter what stimulus is received, you can not physically have another action potential
51
relative refractory period
difficult to have another action potential, need a really big stimulus to move to an even higher threshold since so low.
52
action potentials are regenerated along the axon at points known as
nodes of ranvier
53
each adjacent section is____ and a new action potential occurs
depolarized
54
the axon potential travels inside the axon and jumps from node to node - travel in one direction
saltatory conduction
55
speed of propagation of action potentials, varies with the diameter of the axon - large diameter = faster speed
conduction velocity
56
what speeds up communication
myelin
57
neurotoxin that blocks voltage gated Na and K ion channels
Tetrodotoxin (TTX)
58
Hw does TTX effect action potential?
prevents depolarization of the action potential, no release of neurotransmitters
59
neurotoxin that is irreversible activator of Na channels, affects nerve and muscle cells, stabilizes open conformation of voltage gated ion channels too much Na adding in, depolarization step then plateau
Batrachotoxin (BTX)