Pulmonary System Flashcards
Surfactant is produced by:
Type II alveolar cells
Function of surfactant
Reduces the surface tension of the alveoli and prevent collapse
When does the production of surfactant begin in development?
Week 20
Complete obstruction/blockage/abnormal closure or development of a passage. Due to failure of recanalization of the lumen or incomplete division of the foregut
Atresia
Narrowing/partial closure of a passage. Mainly due to unequal partitioning of the foregut
Stenosis
Abnormal communication/passage due to incomplete division of a tube
Fistula
Germ layer that plays a major role in forming the skull and vertebrae
Paraxial mesoderm
Germ layer that contributes to the urogenital system
Intermediate mesoderm
Germ layer that is involved in forming the body cavity
Lateral plate mesoderm
Type of hernia that is between the xiphoid process and costal margin on the right.
Morgagni’s hernia (retrosternal, parasternal)
-Caused by congenital defect in the fusion of septum transverses of the diaphragm and the costal margin
Hernia due to defective formation or fusion of the pleuroperitoneal membrane
Bochdalek’s hernia (Posterolateral region)
Hernia due to abnormally large esophageal hiatus that causes fundus of stomach to protrude into posterior mediastinum
Congenital hiatal hernia
Eventration of Diaphragm
Half of the diaphragm has defective musculature, causing it to balloon into the thoracic cavity as a membranous sheet, forming a diaphragmatic pouch, and the abdominal viscera are displaced superiorly into the pocket-like outpouching of the diaphragm.
The endoderm lining the respiratory diverticulum gives rise to:
The epithelium and glands of the trachea, bronchi, and alveoli
Mesoderm surrounding the respiratory diverticulum gives rise to:
The connective tissue, cartilage, and smooth muscle of these structures
The epithelial lining of the larynx develops from:
The endoderm of the cranial end of the laryngotracheal tube
Laryngeal cartilages are derived from:
Migration of neural crest cells into the mesenchymal of 4th and 6th pairs of pharyngeal arches
Laryngeal muscles develop from:
Mesenchymal myoblasts from the 4th and 6th pharyngeal arches
The arytenoid swellings are produced from:
The mesenchyme at the cranial end of the laryngotracheal tube rapidly proliferating
The laryngotracheal diverticulum is anterior to the foregut and caudal to which pharyngeal arch?
4th
The ventral division of the tracheoesophageal septum
Laryngotracheal tube
The dorsal division of the tracheoesophageal septum
Oropharynx and esophagus
Week 5-17 lung histological stage
Pseudo-glandular