Lymphatic System-Lecture 25 (Cells) Flashcards
1
Q
What is the first signal for TH (CD4+) cells?
A
i) First signal–when they interact with MHC II-Ag complex
2
Q
TH1 cells synthesize:
A
IFN-gamma, IL2, TNF: activate macrophages to destroy intracellular pathogens
3
Q
TH2 cells synthesize:
A
Synthesize IL4, IL5, IL10, IL13–activate eosinophils, mast cells, and B lymphocytes (for IgE production) to destroy extracellular parasites
4
Q
Perisinusoidal macrophages
A
Kupffer cells
5
Q
Langerhans cells
A
Skin macrophages
6
Q
Dendritic cells
A
Spleen, lymph nodes
7
Q
Non-mononuclear phagocytic system
A
B lymphocytes, Epithelioreticular cells (thymus)
