Psychopharmacology for dentists Flashcards
types of antidepressants
tricyclic antidepressants (TCAs) selective serotonin reuptake inhibitors serotonin and noradrenaline reuptake inhibitors
TCAs
tricyclic antidepressants
inhibits 5-HT and NA uptake
produces therapeutic effect
side effects from block of M1, H1 and alpha 1 receptors
selective serotonin reuptake inhbitors
inhibits 5-HT uptake
therapeutic effect
side effects
- nausea and early anxiety
serotonin and noradrenaline reuptae inhibitors
inhibits 5-HT and NA uptake
therapetuci effect
produces side effects like SSRIs
why would you chose serotonin and NA reuptake inhibitors over the otters 2 antidepressants
better tolerated than TCA
more effective than SSRIs for severe depression
anxiolytics/hypnotics
benxodiazepeines
relive anxiety
what are the drugs of choice for anxiety
antidepressants but take longer to work
types of antipsychotics
1) Typicals/first generation antipsychotics
- e.g. Haloperidol
2) Atypicals/second generation antipsychotics
- E.g. Olanzapine and Risperidone
typical antipsychotics
block D2 receptors
therapeutic effects
what is a mood stabiliser
lithium
narrow therapeutic index
teratogenic
non pharmacologucal approaches
1) Electroconvulsive Therapy (ECT)
2) Phototherapy: seasonal affective disorder
3) Psychological Therapies
4) Social Interventions:
5) Rehabilitation
what can not be used as a mood stabiliser in pregnant women
valproate
teatogenticity
mood stabliser interactions
NSAIDS