pathology of the lower GI tract - 2

Question 1

inflammatory bowel diseases

Answer 1

crohns disease

ulcerative colitis

Question 2

crohns disease

Answer 2

inflamamtion
distributio patchy and anywhere - can affect all layers (music, sub cut fat etc)
can be ulcerative in the mouth
long period of time
- can lead to fibrosis in bowl, cobble store effect

Question 3

ulcerative colitis

Answer 3

only affects colon
starts at rectum and travels up
only affects mucosa
only in the colon max

Question 4

diverticular disease and how does it occur

Answer 4

outpouchings of the musocsa
generally in the sigmoid colon

muscle wall of the bowl has holes to allow blood vessels
with lack of fibre, raised pressure in the bowel
has to squeeze harder to move contents, mucosa pushed towards the muscle layer through the wall (outpouring)

can become inflamed, rupture, faecues from clon can go into periteal cavity and get peritonitis

Question 5

colorectal cancer

Answer 5

adenomas (bening tumour) predisposed to colorectal cancer

Question 6

treatment of colorectal cancer

Answer 6

adenoma (endoscopic resection)
colorectal adenocarcinoma (surgical resection)
metastatic colorectal adenocarcinoma (chemotherapy palliative care)