Liver disease pathology

Question 1

Processes of the liver

Answer 1

all the blood from the gut goes through the liver
liver produces bile, excreted down the bile duct into the duodenum
bile can remove some things, and produce bile salta
gallbladder stores the bile, will release into the duodenum when someone eats

Question 2

jaundice and what causes it

Answer 2

yellowing of skin/eye sclera
too much work for liver o do

can occur in haemolyticc anaemia

Question 3

splenomegaly

Answer 3

enlargement of the spleen

can occur in haemolytic anaemia where the RBCs are being broken down (not as sturdy)

Question 4

cirrhosis

Answer 4

end stage of liver disease
- bands of fibrosis
many nodules on the liver

Question 5

mechanisms of cirrosis

Answer 5

damage to liver cells - inflamamtion
regeneration can occur
but over long period of time, healing by ibrosis

Question 6

causes of cirrohsis

Answer 6

Hepiitis viruses (not A as can revere if virus is clear)
alcohol

Question 7

consequences of cirhosis

Answer 7

liver failure
jaundice
ascites
hepatocellular cancer

Question 8

side effect of cirrhosis and issues

Answer 8

portal hypertension
raised BP in portal syetm
asteomoses and joins can be dilated between portal and venous system
can cause bleeds of the oesophagus

why
- portal vein goes through liver
due to fibrosis, veins tortuoes and blind endins
more pressure required to move the blood through

Question 9

ascites

Answer 9

fluid filled abdomen

due to low albumin production

Question 10

blockage of bile out of the liver

Answer 10

can lead to bladder stones
gallbladder stones if they move into bile duct can block flow of bile into the duodenum
tumours can also block