Gastro intestinal disease/medicine Flashcards

1
Q

functions of GI tract

A

1) turns food into energy
2) waste removal
3) intake of water – hydration

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2
Q

key symptoms associated with GI disfunction

A
vomiting
haematemesis
weiht loss
jaundice
melaena
diarrhoea
abdominal pain
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3
Q

dysphagia

A

difficulty in swallowing

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4
Q

dysphagia problem types

A

oropharyngeal
oesophageal
gastric

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5
Q

history of dysphagia

A
duration
solids or liquids
pain
weight loss
previous MH
medications
SH
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6
Q

oropharyngeal dysphagia

A

difficulty initiating swallowing
difficulty with choking, nasal regurgitation
drooling, hardness etc

after initiation of swallowing at pharynx and upper oesophageal spincter

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7
Q

what can cause oesophageal dysphagia

A
benign musocsal disease
(reflux may be benign peptic structure)
or maligant
or
motility disorder (oesophageal spasm , achalasia, oesophageal pouch)
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8
Q

gastric dysphagia

A

carcinoma
outlet obstruction
peptic ulceration

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9
Q

pharyngeal pouches

A

defect between constrictor and transverse cricopharyges muscle
- due to incoordiantion of swallowing in pharynx, leads to herniation through cricopharyngeal muscle leading to formation of pouch

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10
Q

diagnosis oh pharyngeal poiches

A

barium swallow

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11
Q

management of dysphagia

A

treat underling cause

if nutritionally deplete may need supplementation

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12
Q

what leads to upper abdominal discomfort and cause

A

gastro oesophageal reflux disease

  • excessive relaxation of lower oesophageal sphincter and raised intra abdominal pressure
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13
Q

symptoms of gastro oesophageal reflux discomfort

A
  • heartburn
  • epigastric pain
  • acid reflux
  • waterbrash
  • nausea
  • vomiting
  • tooth decay
  • asthma
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14
Q

management of pts with reflux

A

lifestyle advice (avoid late meals, sleep upright, weight loss, smoking cessation, reduction in alcohol
surgery
H2 agonist (release symptoms)
PPI

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15
Q

PPI examples

A

proton pump inhibitors
omeprazole
lansoprazole

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16
Q

hiatus hernia

A

pressure lost between the abdonomal and thoracic cavities

leads to reflux

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17
Q

types of hiatus hernia

A

prestage
sliding hiatal hernia
paraoesophageal

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18
Q

sliding hiatial hernia

A
  • gastrooesophageal junction and the abdominal part of the oesophagus and cardia of stomach move upwards through diaphragmatic hiatus into the thorax
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19
Q

paraoesophageal hiatal hernia

A
  • upward movement of gastric fundus, normal positioned junction (gastric oesophageal)
    i. e. not all of it moves up, pouch forms above where It should be
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20
Q

diagnosis of peptic ulcers + treamtnet

A

1) test for H pylori and then treat
2) treat patients with active suppression therapy
3) endoscopic therapy if bleeding
4) surgical intervention

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21
Q

types of ulcers and distinguishing

A

gastric- associated with weight loss, worsened by food
haemataesis
duodenal - improve with eating, vomiting

22
Q

what can ulcers be due to

A

helicobacter pylori

non steroidal anti inflammatory drug s

23
Q

what can upper abdominal discomfort be due to

A
gastric carcinoma
ulcer
non ulcer dyspepsia
pacreatic carcinoma
pancreatitis
24
Q

gastric carcinoma history, management and treatment

A
  • epigastric pain, weight loss, vomiting
  • OGD to investigate
  • take biopsies from any areas
  • imaging to stage and assess
    Treatment
  • surgery if possible (gastrectomy)
  • chemotherapy
  • pallative care
25
Q

pancreatic caricnoma

A

unremitting pain
radiates to back
associated with weight loss smoking
may cause jaundice

26
Q

pancreatitis and treatment

A
  • acute inflammation of pancreas causing severe pain, vomiting
  • chronic relapsing pain (chronic pancreatitis)

long term opioids

27
Q

management of acute lower abdominal pain

A

1) surgical referral
2) usually kept NBM
- pts may need surgical intervention
3) IV antibiotics
4) Imaging – USS and CT scan
- assess cause of acute pain

28
Q

what can acute lower abdominal pain be due to

A
  • inflammation (pain develops gradually, diffuse until becoming localised eg acute appendicitis)
  • perforation (starts abruptly, severe and can lead to generalised peritonitis)
  • obstruction (colicy? pain)
29
Q

chronic lower abdominal pain

A

more than 6 weeks
investigate like acute
management analgesics/sugery

30
Q

vomiting causes

A
systemic illness
drug/alcohol
centrala mediated
psychiatric disorders
gastric disease
small bowel disease
colonic diease
31
Q

definition of diarrhoea

A

3 or more loose stools per day/change to normal bowel habit

32
Q

acute causes of diarhoea

A

1) infection
- gastroenteritis: bacterial/viral
- eg campylobacter, salmonella, E coli
- should not last more than 10 days
2) drugs
- antibiotics
- alcohol
3) food allergy/intolerance

33
Q

chronic causes of diarrhoea

A
•	Small bowel disease
–	lactase deficiency
–	Coeliac disease
–	Crohn‘s disease
•	Pancreatic disease
–	pancreatic insufficiency
–	pancreatic carcinoma
–	cystic fibrosis
•	Colonic disease
–	ulcerative colitis
–	Crohn’s disease
–	carcinoma
34
Q

coeliac disease

A

hyperplasia
increased lymphocytes

management
blood test
serology tests to look for ab (when on normal gluten diet)

35
Q

dermatitis herpetiformis

A

ulcers on the body

features when being a coeliac

36
Q

types of diarrhoea and symptoms associated

A
Small bowel/pancreatic
-	pain, floating, difficult to flush
-	throughout day
-	pain variable timing
-	pain not relieved by defecation
Colonic
-	blood and mucus 
-	often in the morning
-	pain related to defecation and relieved on defecation
37
Q

inflammatory bowle diseases

A

crohns disease

ulcerative colitits

38
Q

crohns disease

A

chronic inflammatory disease
affects any part of GI tract
from mouth to perineum
discontinuous

39
Q

ulcerative colitis

A

chronic inflammatory disease invariably affecting the rectum and extending proximal to involve all or part of the colon
continuous inflammation

40
Q

ulcerative colitis symptoms

A

diarrhoea
rectal bleeding
pain
weight loss

41
Q

crohns disease symptoms

A
pain
diarrhoea
weight loss
fever
vomiting
nausea
42
Q

associated diseases of inflammatory diseases

A
  • Skin - erythema nodosum, pyoderma gangrenosum
  • Mouth - ulcers. Crohn’s: lips, buccal mucosa
  • Joints - arthritis, ankylosing spondylitis
  • Eyes - episcleritis, uveitis
  • Vascular - thromboses
  • Liver - cirrhosis, CAH, pericholangitis. U.C: primary sclerosing cholangitis
43
Q

colon cancer symptoms

A
  • none (bowel cancer screening)
  • rectal bleeding
  • altered bowel habits
  • lethargy/weight loss
44
Q

risk factors for cancer seen in the Bowles (colon cancer)

A

polyps

45
Q

investigation and management of colon cancer

A
Investigations
-	colonoscopy
-	barium enema
-	CT
Management
-	evaluate extent of disease
-	if limited to colon – surgical resection possible
-	if not – chemo/radiotherapy 
-	Pala
46
Q

haemorrhoids

A

rectal bleeding
bright red
history of constipation
lasts few days /weeks

47
Q

what is jaundice due to

A

high bilirubin levels

48
Q

post hepatic causes of jaundice

A

gall stones
malignancy
benign biliary structure

49
Q

hepatic causes of jaundice

A

infection
alcohol hepatitis
drugs
decompensaties chronic liver disease

50
Q

pre hepatic causes of jaundice

A

isolated higher bilirubin level

haemolytic anaemia,

51
Q

chronic liver disease signs

A
clubbing 
palmar ertyhema
spider naevei
asicties
tanned appearance