proteins Flashcards
what are proteins?
1 or more polypeptide chains folded into a 3D structure shape
what are the 3 groups in an amino acid?
- amino group
- carboxylic acid group
- residual group
- H atom
what is a polypeptide?
a chain of amino acids help by peptide bonds
how are amino acids bonded together
the carboxyl group from one is bonded via a condensation reaction to the amino group of another to form a peptide bond and make a dipeptide structure
what are the 4 structural stages of a protein?
- primary structure
- secondary structure
- tertiary structure
- quaternary structure
what are the 2 types of proteins?
Globular and fibrous
what is the first stage of protein structure?
Primary:
amino acids are orders
whats is the second stage of protein structure?
secondary:
structure is determined and stabilised by hydrogen bond and some folds appear for example alpha- helix and beta- pleated sheets
whats is the third stage of protein structure?
tertiary:
the overall 3D shape is determined and multiple fold are formed
its now contains 3 types of bonds: ionic, H and disulphide bonds and sometimes hydrophilic and hydrophobic interactions
what happens in the 4th stage of protein structure?
quaternary: when the a polypeptide joins onto another polypeptide
what is the structure of haemoglobin and what is it used for?
- 4x prothetic group called heam
- globular
- 2x alpha subunits
- 2x beta subunits
- carry oxygen in blood
what is the structure of collagen and what is it used for?
- fibrous
- made of 3 polypeptide chains that are around 1000 amino acids long
- a helix shape thats held by H bonds and ionic cross links
- for strength in cartilage, bones, tendons…