Post Streptococcal Glomerulonephritis

Question 1

What type of presentation does post streptococcal glomerulonephritis usually result in?

Answer 1

Usually nephritic syndrome (haematuria)

Question 2

which layer of the membrane does post infectious glomerulonephritis damage?

Answer 2

The endothelial layer

Question 3

when is haematuria investigated in children?

Answer 3

Frank haematuria - straight away.
Microscopic haematuria - after 3 separate positive results.
Microscopic haematuria with proteinuria - straight away.

Question 4

what is a sign of endothelial cell problems?

Answer 4

Frank haematuria

Question 5

what are the most common causes of anti post infection glomerulonephritis?

Answer 5

Usually Group A streptococcus - on throat or skin

Question 6

How does the pathophysiology of post infection occur?

Answer 6

Antigen mimicry - the antigens of group A strep are very common to our natural antigens on the kidney.

Antibody-antigen complexes are deposited onto the kidneys.

Question 7

what is the treatment for post streptococcal glomerulonephritis?

Answer 7

Antibiotics
Supportive renal functions
Diuretics

Question 8

How many people make a full recovery?

Answer 8

80%

some get progressively worse.