chronic diarrhoea r

Question 1

what is short gut syndrome

Answer 1

malabsorption of nutrients
can be due to congenital abnormalities like atresia
can be due to necrotising enterocolitis

Question 2

what is chronic diarrhoea

Answer 2

diarrhoea lasting 4+ weeks

always examine and manage

Question 3

motility disturbance causes of chronic diarrhoea

Answer 3

toddler diarrhoea

IBS

Question 4

active secretion causes of chronic diarrhoea

Answer 4

acute infective disorders

IBD

Question 5

malabsorption causes of chronic diarrhoea

Answer 5

food allergy
coeliac
CF

Question 6

what is osmotic diarrhoea

Answer 6

malabsorption of nutrients creates an osmotic pull

water enters the lumen

Question 7

causes of osmotic diarrhoea

Answer 7

secondary lactase deficiency

transporter defects

Question 8

features of osmotic diarrhoea

Answer 8

lower stool volume
responds to fasting
high osmolarity

Question 9

what is secretory diarrhoea

Answer 9

diarrhoea caused by toxins in gut that increase secretion of water and ions

Question 10

causes of secretory diarrhoea

Answer 10

e coli

cholera

Question 11

features of secretory diarrhoea

Answer 11

doesn’t respond to fasting

electrolytes are high

Question 12

things to ask in history taking

Answer 12

age of onset
abrupt or gradual onset
FH
travel history 
nocturnal defecation - this is always pathological

Question 13

investigations for chronic diarrhoea

Answer 13

growth and weight
faeces appearance
stool culture
stool biochemistry to determine if its osmotic or secretory

Question 14

what could fat malabsorption indicate

Answer 14

pancreatic diseases like CF

hepatobiliary disease like cholestasis