Pharmacogenetics Flashcards

1
Q

how do people respond to drug therapy related to their genetic makeup

A

pharmacogenetics

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2
Q

pharmacogenetics is the same as

A

pharmagonetics

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3
Q

study on how patient genomes affect drug response

A

pharmacogenetics

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4
Q

helps individualize optimal drug treatment regimens

A

pharmacogenetics

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5
Q

help decrease drug reactions

A

pharmacogenetics

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6
Q

promote drug regimen adherence

A

pharmacogenetics

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7
Q

reduces overall healthcare costs

A

pharmacogenetics

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8
Q

what patients benefit from pharmacogenetics?

A
  • those taking multiple prescription drugs
  • those not responding to current therapy
  • those having adverse drug reactions
  • those taking black box warning drugs
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9
Q

what is not available for every drug?

A

pharmacogenetic testing

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10
Q

treats leukemia

A

mercaptopurine

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11
Q

treat colon cancer, small lung cancer. want to eliminate if have genetic variation

A

irinotecan

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12
Q

treat HIV, 10% public has this and its life threatening effects

A

Abacavir

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13
Q

not used widely vitamin K is antagonist, anticoagulant, increases risk of bleeding

A

warfarin

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14
Q

codeine, tramadol (not given in active form). some people don’t have enzyme. 10% to convert this. some don’t have pain control (Asians and middle eastern)

A

opioids

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15
Q

antianalytic, nerve pain, increase immune response and can develop Steven Johnson syndrome

A

carbamazepine

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16
Q

equal and fair treatment for all

A

justice

17
Q

patient may consent to or refuse genetic testing

A

autonomy

18
Q

patient may change mind about testing

A

autonomy