Antidepressants/Mood Stabilizers Flashcards
A mood disorder that causes a persistent feeling of sadness and loss of interest.
Depression
Drugs that treat depression.
Antidepressants
Depression that usually has a sudden onset after a precipitating event
Reactive depression
Deep depression
Dysphoria
A disorder that involves swings between two moods, the manic and the depressive
Bipolar disorder
Drugs that block the uptake of the neurotransmitters norepinephrine and serotonin in the brain. These drugs have more side effects than SSRIs.
Tricyclic antidepressants (TCAs)
Agents that block the reuptake of serotonin into the nerve terminal of the central nervous system
Selective Serotonin Reuptake Inhibitors (SSRIs)
Agents that inhibit the reuptake of serotonin and norepinephrine, increasing availability at the synapse
Serotonin Norepinephrine Reuptake Inhibitors
Drugs used for major depression, reactive depression, and anxiety that affect one or two of the three neurotransmitters.
Atypical antidepressants
Agents that inactivate norepinephrine, dopamine, epinephrine, and serotonin
Monoamine oxidase inhibitors (MAOIs)
Amitriptyline, imipramine, trimipramine, desipramine, doxepin, nortriptyline, and protriptyline are which type of drugs?
TCAs
True of False: Patients with glaucoma may take TCAs.
False
True or False: Patients must taper off of antidepressant drugs rather than stopping them abruptly.
True
Do TCAs cause hypertension or orthostatic hypotension?
Orthostatic hypotension
True or False: It is better for patients to take TCAs first thing in the morning.
False
Fluoxetine, Sertraline, Paroxetine, Citalopram, and Escitalopram are examples of which kind of drugs?
SSRIs
True of False: SSRIs can cause patients to have increased suicidal ideation.
True
Is it better to take SSRIs in the morning or evening?
Morning
Venlafaxine, Duloxetine, and Desvenlafaxine are which type of drugs?
SNRIs
Taking SNRIs and St. John’s Wort can cause what?
Serotonin syndrome and neuroleptic malignant syndrome
True or False: SNRIs can cause damage to the liver.
True
True or False: MAOIs can be taken along with other antidepressants.
False
Amoxapine, maprotiline, and trazadone are which type of drugs?
Atypical antidepressants
Tranylcyclopromine, isocarboxazid, selegiline, and phenylzine are which type of drugs?
MAOIs
Foods high in what should be avoided when taking MAOIs?
Tyramine
What foods are high in tyramine?
Some cheeses, cream, yogurt, chocolate, bananas, raisins, Italian green beans, liver, pickled foods, sausage, soy sauce, yeast, beer, and red wines.
Lithium is what kind of drug?
Mood stabilizer
The therapeutic range for lithium is:
0.8 - 1.2 mEq/L
Lithium can deplete which electrolyte?
Sodium
Early signs of lithium toxicity include:
Diarrhea, drowsiness, vomiting, slurred speech, trembling
Late signs of lithium toxicity include:
Blurred vision, confusion, large urine output, convulsions
What can decrease lithium levels?
Caffeine and loop diuretics
What herb should not be taken with anti depression meds?
St. Johns Wort
Ginko bilboa
