Anticoagulants, Antiplatelets, and Thrombolytics Flashcards
Clumping together of platelets to form a clot
Aggregation
The formation of a clot in an arterial or venous vessel
Thrombosis
Prevent the formation of clots that inhibit circulation
Anticoagulants
Used to prevent thrombosis in the arteries by suppressing platelet aggregation
Antiplatelets
A clot in a blood vessel
Thromboembolism
Deficient blood flow
Ischemia
Agents used to promote the fibrinolytic mechanism (converting fibrinogen to plasmin, which destroys the fibrin in a blood clot)
Thrombolytics
Fibrin breakdown
Fibrinolysis
The 3 types of drugs we use to maintain and restore circulation are:
Anticoagulants, antiplatelets, and thrombolytics
True or False: A venous thrombus can form due to slow blood flow.
True
Signs and symptoms of pulmonary embolism include:
Decreased oxygen saturation, chest pain, shortness of breath, and hemoptysis.
Heparin, enoxaparin, and warfarin are what?
Anticoagulants
True or False: Heparin and enoxaparin are often given orally.
False
Which drug has a longer half-life, heparin or enoxaparin?
Enoxaparin
What labs should be monitored when a person is on IV heparin?
PTT and aPTT
What is the antidote to heparin?
Protamine sulfate
True or False: Frequent lab monitoring is not required for the patient on enoxaparin.
True
Dabiitran, Rivaroxaban, and Apixaban are what type of drugs?
Direct thrombin inhibitors
What labs need to be monitored for a patient on warfarin?
PT and INR
What is the antidote to warfarin?
Vitamin K
Besides vitamin K, what else will we give to a patient on warfarin who has an active bleed?
Fresh frozen plasma or platelets
True or False: Patients on warfarin should increase the green leafy vegetables in their diet.
False
Aspirin and clopidogrel are which type of drugs?
Antiplatelet
True or False: Clopidogrel can cause peptic ulcers.
True
Alteplase and Tenecteplase are which type of drugs?
Thrombolytics
What is the antidote for thrombolytics?
Aminocaproic acid
