Anticoagulants, Antiplatelets, and Thrombolytics

Question 1

Clumping together of platelets to form a clot

Answer 1

Aggregation

Question 2

The formation of a clot in an arterial or venous vessel

Answer 2

Thrombosis

Question 3

Prevent the formation of clots that inhibit circulation

Answer 3

Anticoagulants

Question 4

Used to prevent thrombosis in the arteries by suppressing platelet aggregation

Answer 4

Antiplatelets

Question 5

A clot in a blood vessel

Answer 5

Thromboembolism

Question 6

Deficient blood flow

Answer 6

Ischemia

Question 7

Agents used to promote the fibrinolytic mechanism (converting fibrinogen to plasmin, which destroys the fibrin in a blood clot)

Answer 7

Thrombolytics

Question 8

Fibrin breakdown

Answer 8

Fibrinolysis

Question 9

The 3 types of drugs we use to maintain and restore circulation are:

Answer 9

Anticoagulants, antiplatelets, and thrombolytics

Question 10

True or False: A venous thrombus can form due to slow blood flow.

Answer 10

True

Question 11

Signs and symptoms of pulmonary embolism include:

Answer 11

Decreased oxygen saturation, chest pain, shortness of breath, and hemoptysis.

Question 12

Heparin, enoxaparin, and warfarin are what?

Answer 12

Anticoagulants

Question 13

True or False: Heparin and enoxaparin are often given orally.

Answer 13

False

Question 14

Which drug has a longer half-life, heparin or enoxaparin?

Answer 14

Enoxaparin

Question 15

What labs should be monitored when a person is on IV heparin?

Answer 15

PTT and aPTT

Question 16

What is the antidote to heparin?

Answer 16

Protamine sulfate

Question 17

True or False: Frequent lab monitoring is not required for the patient on enoxaparin.

Answer 17

True

Question 18

Dabiitran, Rivaroxaban, and Apixaban are what type of drugs?

Answer 18

Direct thrombin inhibitors

Question 19

What labs need to be monitored for a patient on warfarin?

Answer 19

PT and INR

Question 20

What is the antidote to warfarin?

Answer 20

Vitamin K

Question 21

Besides vitamin K, what else will we give to a patient on warfarin who has an active bleed?

Answer 21

Fresh frozen plasma or platelets

Question 22

True or False: Patients on warfarin should increase the green leafy vegetables in their diet.

Answer 22

False

Question 23

Aspirin and clopidogrel are which type of drugs?

Answer 23

Antiplatelet

Question 24

True or False: Clopidogrel can cause peptic ulcers.

Answer 24

True

Question 25

Alteplase and Tenecteplase are which type of drugs?

Answer 25

Thrombolytics

Question 26

What is the antidote for thrombolytics?

Answer 26

Aminocaproic acid