Pharm 1 Liner- Autonomics

Question 1

Beta blockers with partial agonist activity, can bronchodilator and may have an advantage treating patients with asthma (2)

Answer 1

Pindolol, acebutolol

Question 2

Indicated for symptomatic orthostatic hypotension

Answer 2

Midodrine

Question 3

Antimuscarinic for prophylaxis of motion sickness

Answer 3

Scopolamine

Question 4

Beta blockers effect on the heart in antianginal therapy (6)

Answer 4

Reduce heart rate, blood pressure, contractility, myocardial oxygen consumption, increase ejection time, and no change or increase end diastolic volume

Question 5

Blocks alpha 1 and beta receptors and indicated for treatment of CHF

Answer 5

Labetalol and carvedilol

Question 6

Its ability to vasoconstrict and increase blood pressure makes it useful as local decongestant and for the therapy of spinal shock (temporary maintenance of blood pressure)

Answer 6

Alpha 1 agonists

Question 7

Treatment of myasthenia gravis and sometimes used prophylactically for organophosphate poisoning in chemical warfare

Answer 7

Pyridostigmine

Question 8

Organophosphate, indicated for glaucoma but not used much clinically due to long duration of action

Answer 8

Echothiophate

Question 9

Alpha 1a-selective blocker used for BPH

Answer 9

Tamsulosin

Question 10

A non-selective beta blocker with alpha 1 blocking effect indicated for CHF

Answer 10

Carvedilol

Question 11

Beta blockers are used for this type of angina attack

Answer 11

Classic (exertional) angina

Question 12

Beta blockers should be used cautiously in (3)

Answer 12

Asthma (bronchospastic effects), diabetics (block signs of hypoglycemia), and peripheral vascular disease

Question 13

Toxicity caused by this class of drugs is chars by DUMBELSS (diarrhea, urination, miosis, bronchoconstriction, excitation of skeletal muscle and CNS, lacrimation, salivation, sweating)

Answer 13

Cholinergic drugs

Question 14

Indirect acting sympathomimetic, improves urinary continence in children and elderly with enuresis

Answer 14

Ephedrine

Question 15

Short acting beta blocker that can be given parenterally, commonly used in hemodynamically unstable patients

Answer 15

Esmolol

Question 16

Beta 1 agonist toxicity (2)

Answer 16

Sinus tachycardia and serious arrhythmia

Question 17

Contraindications to use atropine (3)

Answer 17

Infants, closed angle glaucoma, prostatic hypertrophy

Question 18

Its ability to increase heart rate makes it useful as adjunct therapy for acute herat failure and hypovolemia or septic shock

Answer 18

Beta 1 agonist

Question 19

Muscarinic selective cholinomimetic used to diagnose asthma

Answer 19

Methacholine

Question 20

Longer acting beta 2 agonist, indicated for prophylaxis of asthma

Answer 20

Slameterol

Question 21

Alpha agonist indicated for nasal congestion, hypotension, and mydriasis induction

Answer 21

Phenylephrine

Question 22

Indirect acting sympathomimetic, reuptake inhibitor, commonly abused, indicated for attention deficit disorder and weight reduction

Answer 22

Methaphetamine

Question 23

Insecticide organophosphate

Answer 23

Malathion, parathion

Question 24

Beta agonist used in acute CHF

Answer 24

Dobutamine and dopamine

Question 25

Drug of choice for anaphylactic shock

Answer 25

Epinephrine

Question 26

Anti muscarinic that produces mydriasis and cycloplegia

Answer 26

Atropine and anti-muscarinics

Question 27

Irreversible, non-selective alpha-blocker indicated for pheochromocytoma

Answer 27

Phenoxybenzamine

Question 28

Short acting beta 2 agonist, drug of choice for acute asthma

Answer 28

Albuterol

Question 29

Selective beta 1 receptor blockers useful for treating cardiac conditions in patients with asthma (5)

Answer 29

Acebutolol, betaxolol, esmolol, atenolol, metoprolol (A BEAM)

Question 30

Pneumonic for beta receptors

Answer 30

You have 1 heart (beta 1) and 2 lungs (beta 2)

Question 31

This agent has greater affinity for muscarinic receptors and used for postoperative and neurogenic ileus and urinary retention

Answer 31

Bethanechol

Question 32

Atropine fever is the most dangerous effect and can be lethal in this population group

Answer 32

Infants

Question 33

Selective alpha 1 blocker used for HTN, BPH, may cause first dose orthostatic Hypotension (3)

Answer 33

Prazosin, terazosin, doxazosin

Question 34

Alpha 1 agonist toxicity

Answer 34

Hypertension

Question 35

The most important cause of acute deaths in cholinesterase inhibitor toxicity

Answer 35

Respiratory failure

Question 36

Beta 2 agonist adverse effect

Answer 36

Skeletal muscle tremor

Question 37

Mechanism of action of atropine

Answer 37

Non-selective antimuscarinic

Question 38

Beta 2 agonist used to suppress premature labor, but cardiac stimulatory effects may be hazardous to mother and fetus

Answer 38

Terbutaline

Question 39

Reversible, non-selective alpha blocker indicated for pheochromocytoma

Answer 39

Phentolamine

Question 40

Antimuscarinic that treats Parkinsonism and extrapyramidal disease

Answer 40

Benztropine

Question 41

Alkaloid muscarinic that is very lipid soluble and used in glaucoma

Answer 41

Pilocarpine

Question 42

Used in treatment of muscarinic symptoms in organophosphate overdose

Answer 42

Atropine

Question 43

Cholinesterase inhibitor, intermediate duration of action, used off label for postoperative paralytic ileus and urinary retention

Answer 43

Neostigmine

Question 44

Antimuscarinic indicated for overactive bladder muscle dysfunction

Answer 44

Oxybutynin

Question 45

Side effects of beta blockers

Answer 45

Bradycardia, AB block, impotence, dyslipidemia, exacerbation of COPD

Question 46

Cholinesterase inhibitor, short duration of action, used in diagnosis of myasthenia gravis

Answer 46

Edrophonium

Question 47

Antimuscarinic that causes bronchodilation in asthma and COPD (2)

Answer 47

Ipatropium, tiotropium

Question 48

Non-selective beta blocker that lacks local anesthetic activity, indicated for glaucoma

Answer 48

Timolol

Question 49

Muscarinic used to treat dry mouth in Sjögren's syndrome

Answer 49

Pilocarpine or cevimeline

Question 50

Cholinesterase inhibitor, lipid soluble, indicated for atropine overdose and glaucoma

Answer 50

Physostigmine