Pharm 1 Liner- Autonomics Flashcards
Beta blockers with partial agonist activity, can bronchodilator and may have an advantage treating patients with asthma (2)
Pindolol, acebutolol
Indicated for symptomatic orthostatic hypotension
Midodrine
Antimuscarinic for prophylaxis of motion sickness
Scopolamine
Beta blockers effect on the heart in antianginal therapy (6)
Reduce heart rate, blood pressure, contractility, myocardial oxygen consumption, increase ejection time, and no change or increase end diastolic volume
Blocks alpha 1 and beta receptors and indicated for treatment of CHF
Labetalol and carvedilol
Its ability to vasoconstrict and increase blood pressure makes it useful as local decongestant and for the therapy of spinal shock (temporary maintenance of blood pressure)
Alpha 1 agonists
Treatment of myasthenia gravis and sometimes used prophylactically for organophosphate poisoning in chemical warfare
Pyridostigmine
Organophosphate, indicated for glaucoma but not used much clinically due to long duration of action
Echothiophate
Alpha 1a-selective blocker used for BPH
Tamsulosin
A non-selective beta blocker with alpha 1 blocking effect indicated for CHF
Carvedilol
Beta blockers are used for this type of angina attack
Classic (exertional) angina
Beta blockers should be used cautiously in (3)
Asthma (bronchospastic effects), diabetics (block signs of hypoglycemia), and peripheral vascular disease
Toxicity caused by this class of drugs is chars by DUMBELSS (diarrhea, urination, miosis, bronchoconstriction, excitation of skeletal muscle and CNS, lacrimation, salivation, sweating)
Cholinergic drugs
Indirect acting sympathomimetic, improves urinary continence in children and elderly with enuresis
Ephedrine
Short acting beta blocker that can be given parenterally, commonly used in hemodynamically unstable patients
Esmolol
Beta 1 agonist toxicity (2)
Sinus tachycardia and serious arrhythmia
Contraindications to use atropine (3)
Infants, closed angle glaucoma, prostatic hypertrophy
Its ability to increase heart rate makes it useful as adjunct therapy for acute herat failure and hypovolemia or septic shock
Beta 1 agonist
Muscarinic selective cholinomimetic used to diagnose asthma
Methacholine
Longer acting beta 2 agonist, indicated for prophylaxis of asthma
Slameterol