Pharm 1 Liner- Autonomics Flashcards

1
Q

Beta blockers with partial agonist activity, can bronchodilator and may have an advantage treating patients with asthma (2)

A

Pindolol, acebutolol

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2
Q

Indicated for symptomatic orthostatic hypotension

A

Midodrine

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3
Q

Antimuscarinic for prophylaxis of motion sickness

A

Scopolamine

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4
Q

Beta blockers effect on the heart in antianginal therapy (6)

A

Reduce heart rate, blood pressure, contractility, myocardial oxygen consumption, increase ejection time, and no change or increase end diastolic volume

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5
Q

Blocks alpha 1 and beta receptors and indicated for treatment of CHF

A

Labetalol and carvedilol

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6
Q

Its ability to vasoconstrict and increase blood pressure makes it useful as local decongestant and for the therapy of spinal shock (temporary maintenance of blood pressure)

A

Alpha 1 agonists

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7
Q

Treatment of myasthenia gravis and sometimes used prophylactically for organophosphate poisoning in chemical warfare

A

Pyridostigmine

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8
Q

Organophosphate, indicated for glaucoma but not used much clinically due to long duration of action

A

Echothiophate

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9
Q

Alpha 1a-selective blocker used for BPH

A

Tamsulosin

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10
Q

A non-selective beta blocker with alpha 1 blocking effect indicated for CHF

A

Carvedilol

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11
Q

Beta blockers are used for this type of angina attack

A

Classic (exertional) angina

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12
Q

Beta blockers should be used cautiously in (3)

A

Asthma (bronchospastic effects), diabetics (block signs of hypoglycemia), and peripheral vascular disease

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13
Q

Toxicity caused by this class of drugs is chars by DUMBELSS (diarrhea, urination, miosis, bronchoconstriction, excitation of skeletal muscle and CNS, lacrimation, salivation, sweating)

A

Cholinergic drugs

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14
Q

Indirect acting sympathomimetic, improves urinary continence in children and elderly with enuresis

A

Ephedrine

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15
Q

Short acting beta blocker that can be given parenterally, commonly used in hemodynamically unstable patients

A

Esmolol

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16
Q

Beta 1 agonist toxicity (2)

A

Sinus tachycardia and serious arrhythmia

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17
Q

Contraindications to use atropine (3)

A

Infants, closed angle glaucoma, prostatic hypertrophy

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18
Q

Its ability to increase heart rate makes it useful as adjunct therapy for acute herat failure and hypovolemia or septic shock

A

Beta 1 agonist

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19
Q

Muscarinic selective cholinomimetic used to diagnose asthma

A

Methacholine

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20
Q

Longer acting beta 2 agonist, indicated for prophylaxis of asthma

A

Slameterol

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21
Q

Alpha agonist indicated for nasal congestion, hypotension, and mydriasis induction

A

Phenylephrine

22
Q

Indirect acting sympathomimetic, reuptake inhibitor, commonly abused, indicated for attention deficit disorder and weight reduction

A

Methaphetamine

23
Q

Insecticide organophosphate

A

Malathion, parathion

24
Q

Beta agonist used in acute CHF

A

Dobutamine and dopamine

25
Q

Drug of choice for anaphylactic shock

A

Epinephrine

26
Q

Anti muscarinic that produces mydriasis and cycloplegia

A

Atropine and anti-muscarinics

27
Q

Irreversible, non-selective alpha-blocker indicated for pheochromocytoma

A

Phenoxybenzamine

28
Q

Short acting beta 2 agonist, drug of choice for acute asthma

A

Albuterol

29
Q

Selective beta 1 receptor blockers useful for treating cardiac conditions in patients with asthma (5)

A

Acebutolol, betaxolol, esmolol, atenolol, metoprolol (A BEAM)

30
Q

Pneumonic for beta receptors

A

You have 1 heart (beta 1) and 2 lungs (beta 2)

31
Q

This agent has greater affinity for muscarinic receptors and used for postoperative and neurogenic ileus and urinary retention

A

Bethanechol

32
Q

Atropine fever is the most dangerous effect and can be lethal in this population group

A

Infants

33
Q

Selective alpha 1 blocker used for HTN, BPH, may cause first dose orthostatic Hypotension (3)

A

Prazosin, terazosin, doxazosin

34
Q

Alpha 1 agonist toxicity

A

Hypertension

35
Q

The most important cause of acute deaths in cholinesterase inhibitor toxicity

A

Respiratory failure

36
Q

Beta 2 agonist adverse effect

A

Skeletal muscle tremor

37
Q

Mechanism of action of atropine

A

Non-selective antimuscarinic

38
Q

Beta 2 agonist used to suppress premature labor, but cardiac stimulatory effects may be hazardous to mother and fetus

A

Terbutaline

39
Q

Reversible, non-selective alpha blocker indicated for pheochromocytoma

A

Phentolamine

40
Q

Antimuscarinic that treats Parkinsonism and extrapyramidal disease

A

Benztropine

41
Q

Alkaloid muscarinic that is very lipid soluble and used in glaucoma

A

Pilocarpine

42
Q

Used in treatment of muscarinic symptoms in organophosphate overdose

A

Atropine

43
Q

Cholinesterase inhibitor, intermediate duration of action, used off label for postoperative paralytic ileus and urinary retention

A

Neostigmine

44
Q

Antimuscarinic indicated for overactive bladder muscle dysfunction

A

Oxybutynin

45
Q

Side effects of beta blockers

A

Bradycardia, AB block, impotence, dyslipidemia, exacerbation of COPD

46
Q

Cholinesterase inhibitor, short duration of action, used in diagnosis of myasthenia gravis

A

Edrophonium

47
Q

Antimuscarinic that causes bronchodilation in asthma and COPD (2)

A

Ipatropium, tiotropium

48
Q

Non-selective beta blocker that lacks local anesthetic activity, indicated for glaucoma

A

Timolol

49
Q

Muscarinic used to treat dry mouth in Sjögren’s syndrome

A

Pilocarpine or cevimeline

50
Q

Cholinesterase inhibitor, lipid soluble, indicated for atropine overdose and glaucoma

A

Physostigmine