images for denise

Question 1

Answer 1

Atypical lymphocyte (EBV)

Question 2

Answer 2

Blasts of acute leukemia

Question 3

Answer 3

AML with auer rods

Question 4

Answer 4

Chronic lymphocytic leukemia (B cells that express CD 5 and 20)

Question 5

Answer 5

Hairy cell leukemia

Question 6

Answer 6

Sezary cells (mycosis funoides)

Question 7

Answer 7

Chronic myelogenous leukemia

Question 8

Answer 8

Essential thrombocytopenia

Question 9

Answer 9

Teardrop RBC of myelofibrosis

Question 10

Answer 10

Starry Sky of burkitt lymphoma

Question 11

Answer 11

Reed-Sternberg in Hodgkin Lymphoma

Question 12

Answer 12

Rouleux formation - Mulitple myeloma

Question 13

Answer 13

Birbeck granule - Langerhans cell histocytosis

Question 15

Answer 15

Homer Wright Rosettes (medulloblastoma)

Question 16

Answer 16

Signet Ring cells (gastric carcinoma)

Question 17

Answer 17

Call-Exner bodies (granulosa tumor of ovary)

Question 18

Answer 18

Curschmann Spiral (bronchial asthma)

Question 19

Answer 19

Koilocyte (HPV)

Question 20

Answer 20

Owl Eye (EBV)

Question 21

Answer 21

Orphan Annie Eyes (papillary carcinoma of thyroid)

Question 22

Answer 22

Mallory Body (alcoholic liver disease)

Question 23

Answer 23

Lewy Body (parkinsons, lewy body dementia)

Question 24

Answer 24

Councilman body (hepatocyte undergoing apoptosis)

Question 25

Answer 25

Negri body (rabies)

Question 26

Answer 26

Schiller-Duval bodies (yolk sac tumor)

Question 27

Biopsy of myocardium

Answer 27

Aschoff bodies (rheumatic fever)

Question 28

Sputum culture

Answer 28

Charcot-Leyden crystal (asthma)

Question 29

Answer 29

Cowdry type A bodies (HSV or VZV)

Question 30

Answer 30

Ferruginous bodies (asbestosis)

Question 31

Answer 31

String sign (Crohns)

Question 32

Answer 32

Neurofibrillay tangles (hyperphosphorylated tau; alzheimers)

Question 33

Answer 33

Pick bodies (tau, pick disease)

Question 34

Answer 34

Clue cell (gardnerella vaginalis)

Question 35

Answer 35

Celiac

Question 36

Answer 36

GBM

Astrocytes, crosses midline, pseudopalisading, malignant

Question 37

Answer 37

Aspergillis fumigatis

Question 38

Answer 38

Fusion of basal ganglia in holoprosencephaly

Question 39

Answer 39

Chromatolysis in axonal injury (round cellular swelling)

Question 40

Answer 40

Epidural hematoma: biconvex (lentiform)

Question 41

Answer 41

Subdural hematoma

Red: cresecent shapped hemorrhage

Blue: acute on chronic

Question 42

Answer 42

Lewy bodies of Parkinson (composed of α-synuclein)

Question 43

Answer 43

Senile plaques in Alzheimer (extracellular β-amyloid core)

Question 44

Answer 44

Neurofibriallry tangle (tau) in Alzheimer; # of tangles correlates well to disease progression

Question 45

Answer 45

Pick bodies (tau)

Question 46

Answer 46

Prions in Creutzfeldt-Jakob disease

Question 47

Answer 47

“Pseudopalisading”; Glioblastoma multiforme

Question 48

Answer 48

“Fried egg” cells— round nuclei with clear cytoplasm: Oligodendroglioma

Question 49

Answer 49

psammoma bodies: Meningioma

Question 50

Answer 50

Hemangioblastoma: cerebellar

Question 51

Seen on bone marrow biopsy

Answer 51

• Bone marrow infiltrated by plasma cells: abundant basophilic cytoplasm, eccentric nuceli, wagon wheel/clock face nuclear chromatin
• Indicative of multiple myeloma (>30% plasma cells)

Question 52

Seen on lymph node biopsy

Answer 52

• Follicular lymphoma (subtype of NHL)
  
  • tumor composed of centrocytes
• Aggregates of packed follicles, obscuring normal architecture
• t(14;18): overexpression of BCL-2

Question 53

Answer 53

• Neuroendocrine cell tumor (carcinoid tumor)
  
  • uniform cells that form islands
  • Eosinophilic cytoplasm
  • Oval-round nuclei
• Neuroendocrine tumors often cause appendicitis

Question 54

Seen on bone marrow aspiration

Answer 54

• Gaucher cells: lipid laden macrophages
  
  • AR
  • B-glucocerebrosidase deficiency

Question 55

Seen on blood smear

Answer 55

• Hereditary spherocytosis
  
  • AD; defect in ankryin or spectrin
    *

Question 56

Answer 56

• Enterocytes with clear/foamy cytoplasm at tips: lipid accumulation
• Seen in abetalipoproteinemia
  
  • AR LoF of MTP

Question 57

Answer 57

• Neurofibromas and cafe au lait (on the left side)
• NF-1
  
  • AD
    *

Question 59

Pt with history of smoking and job in construction has this on their sputum culture. What cancer is most likely?

Answer 59

Bronchogenic (>>mesothelioma)

This are feruginous bodies