key association Flashcards
actinic (solar) keratosis
percursor to squamous cell carcinoma
acute gastric ulcer associated with CNS injury
cushing ulcer (increased intracranial pressure stimulates vagal gastric H+ secretion)
acute gastric ulcer associated with severe burns
curling ulcer (greatly reduced plasma volume results in sloughing of gastric mucosa
age ranges for patients with ALL/CLL/AML/CML
ALL=child; CLL=adult over 60; AML=adult roughly 65; CML=adult 45-85
alternating areas of transmural inflammation and normal colon
skip lesions (crohn disease)
aortic aneurysm, abdominal
atherosclerosis
aortic aneurysm, ascending or arch
tertiary syphilis, vasa vasorum destruction
aortic aneurysm, thoracic
marfan syndrome
aortic dissection
hypertension
atrophy of the mammillary bodies
wernicke encephalopathy
autosplenectomy (fibrosis and shrinkage)
sick cell disease
bacteria associated with gastritis, PUD, and gastric malignancies
H pyori
bacterial meningitis (adults and elderly)
S. pneumoniae
bacterial meningitis (newborns and kids)
group B streptococcus/E.coli/listeria monocytopgenes (new borns), Spneumoniae/N. meningitidis (kinds/teens)
bilateral ovarian metastases from gastric carcinoma
krukenberg tumor
bleeding disorder with GpIb deficiency
bernard-soulier syndrome (defect in platelet adhesion to von willebrand factor)
brain tumors (adults)
supratentorial; metastasis, astrocytoma (including glioblastoma multiforme), meningioma, schwannoma
brain tumor (kids)
infratentorial: medulloblasotma (cerebellum) or supratentorial: craniopharyngioma
breast cancer
invasive ductal carcinoma
breast mass
fibrocystic change, carcinoma (in postmenopausal women)
breast tumor (being, young women)
fibroadenoma
cardiac primary tumor (kids)
rhabdomyoma, often seen in tuberous sclerosis
cardiac manifestation of lupus
marantic/thrombotic endocarditis (non-bacterial)
cardiac tumor (adults)
metastasis, myxoma
cerebellar tonsillar herniation
chiari I malformation
chronic arrhythmia
atrial fibrillation
chronic atrophic gastritis (autoimmune)
predisposition to gastric carcinoma (can also cause pernicious anemia)
clear cell adenocarcinoma of the vagina
DES exposure in utero
congenital adrenal hyperplasia, hypotension
21-hydroxylase deficiency
congenital cardiac anomaly
VSD
congenital conjugated hyperbilirubinemia (black liver)
dubin johnson syndrome
constructive pericarditis
TB; idiopathic, viral illness
cretinism
iodine deficit/congenital hypothyroidism
cyanosis
tetralogy of ballot, transposition of great vessels, trunks arteriosus
death in CML
blast crisis
death in SLE
lupus nephropathy
demyelinating disease in young women
multiple sclerosis
DIC
severe sepsis, obstetric complications, cancer, burns, trauma, major surgery, acute pancreatitis, APL
diverticulum in pharynx
zener diverticulum
ejection click
aortic stenosis
esophageal cancer
squamous cell carcinoma (worldwide); adenocarcinoma (US)
food poisoning (exotoxin mediated)
S aureus, B cereus
gastric cancer
adenocarcinoma
glomerulonephritis (adults)
berger disease (IgA nephropathy)
gynecologic malignancy
endometrial carcinoma (most common in US); cervical carcinoma (most common worldwide)
heart murmur, congenital
mitral valve prolapse
heart valve in bacterial endocarditis
mitral>aortic (rheumatic fever), tricuspid (IV drug abuse)
helminth infection (US)
ascaris lumbricoides
hematoma-epidural
rupture of middle meningeal artery
hematoma- subdural
rupture of riding veins
hemochromatosis
multiple blood transfusions or hereditary HFE mutation
hepatocellular carcinoma
cirrhotic liver
hereditary bleeding disorder
von willebrand disease
hereditary harmless jaundice
gilbert syndrome
HLA-B27
psoriatic arthritis, ankylosing spondylitis, IBD-associated arthritis, reactive arthritis
HLA-DR3
DM type 1, SLE, graves disease, hashimoto thyroiditis, addisons disease
HLA-DR4
DM type 1, rheumatoid arthritis, addisons disease
holosystolic murmur
VSD, tricuspid regurgitation, mitral regurgitation
hyper coagulability, endothelial damage, blood stasis
birches triad
hypoparathyroidism
accidental excision during thyroidectomy
hypopituitarism
pituitary adenoma (usually benign tumor)
infection secondary to blood transfusion
HepC
infection in chronic granulomatous disease
S. aureus, E.coli, aspergillus
intellectual disability
down syndrome, fragile X syndrome
late cyanotic shunt (uncorrected eft to right becomes right to left)
eisenmenger syndrome
liver disease
alcoholic cirrhosis
lysosomal storage disease
gaucher disease
malignancy associated with noninfectious fever
Hodgkin lymphoma
malignancy (kids)
leukemia, brain tumors
metastasis to brain
lung > brain > prostate > melanoma > GI
metastases to liver
colon > stomach > pancreas
mitochondrial inheritance
disease occurs in both males and females, inherited through females only
mitral valve stenosis
rheumatic heart disease
mixed (UMN and LMN) motor neuron disease
amyotrophic lateral sclerosis
myocarditis
coxsackie B
nephrotic syndrome (adults)
membranous nephropathy
nephrotic syndrome (kids)
minimal change disease
neuron migration failure
kallmann syndrome
obstruction of male urinary tract
BPH
opening snap
mitral stenosis
opportunistic infection in AIDS
pneumocystis jirovecii pneumonia
osteomyelitis
S aureus
osteomyelitis in sickle cell disease
Salmonella
osteomyelitis with IV drug use
pseudomonas, candida, S.aureus
ovarian tumor (benign, bilateral)
serous cystadenoma
ovarian tumor (malignant)
serous cystadenocarcinoma
pancreatitis (acute)
gallstones, alcohol
philadelphia chromosome t(9;22) (BCR-ABL)
CML
pituitary tumor
prolactinoma, somatotropin adenoma
primary amenorrhea
turner syndrome
primary bone tumor (adults)
multiple myeloma
refractory peptic ulcer and high gastrin levels
zollinger-ellison syndrome, associated with MEN1
right heart failure due to a pulmonary cause
cor pulmonale
S3 heart sound
increased ventricular filling pressure (mitral regurgitation, HF), common in dilated ventricles
S4 heart sound
Stiff/hypertrophic ventricles (aortic stenosis, restrictive cardiomyopathy)
secondary hyperparathyroidism
hypocalcemia of chronic kidney disease
SIADH
small cell carcinoma of lung
site of diverticula
sigmoid colon
sites of atherosclerosis
abdominal aorta > coronary artery > popliteal artery > carotid artery
t(14;18)
follicular lymphomas
t(8;14)
burrkitt lymphoma
temporal arteritis
risk of ipsilateral blindness due to occlusion of ophthalmic artery, polymyalgia rheumatic
tumor in women
leiomyoma
tumor of adrenal medulla (adults)
pheochromocytoma (usually benign)
tumor of the adrenal medulla (kids)
neuroblastoma (malignant)
type of non-hodgkin lymphoma
diffuse large B-cell lymphoma
viral encephalitis affecting temporal lobe
HSV-1