Peptic Ulcer Disease: Pharmacological Management

Question 1

Hyposecretory Drugs

Answer 1

1. H2RA
2. PPI
3. Prostaglandin Analogues

Question 2

Decreases gastric secretion, increases resistance of mucosa to injury

Answer 2

Prostaglandin Analogues
1. Misoprostol (Cytotec)

Question 3

Action: forms a seal over the ulcer, protecting it from irritation

Answer 3

Mucosal Barrier Protectants
1. Sucralfate

Question 4

• antidiarrheal, suppresses H. pylori in the gastric mucosa and assists with the healing of mucosal ulcers
• taken on an empty stomach
• may darken stool

Answer 4

Bismuth Salicylate