Liver Cirrhosis: Pharmacological Management

Question 1

Pharmacological Management

Answer 1

1. Antacid or H2RA
2. Spironolactone (K sparing diuretics)
3. Furosemide
4. Vitamin K
5. Colchicine
6. Silybum marianum
7. IV Albumin
8. Duphalac (Lactulose)
9. Neomycin sulfate

Question 2

To decrease gastric distress and to prevent GI bleeding

Answer 2

Antacids or H2RA

Question 3

Diuretic of choice to manage ascites
Does not cause hypokalemia

Answer 3

Spironolactone

Question 4

Diuretic given if pt (+) hyperkalemia after prolonged use of spironolactone

Answer 4

Furosemide

Question 5

Prevents bleeding tendencies

Answer 5

Vitamin K

Question 6

Possess antifibrotic activity; to lessen the severity of scarring

Answer 6

Colchicine

Question 7

Reduces levels of ammonia produced by bacteria in the bowel and facilitates excretion of ammonia

Answer 7

Duphalac (Lactulose)

Question 7

For healing and regenerative property; manage scarring of liver

Treatment of toxic hepatitis, fatty liver, cirrhosis, ischemic injury, radiation toxicity, and viral hepatitis

It is a strong antioxidant capable of scavenging unconjugated radicals

Answer 7

Silybum marianum (herb milk thistle)

Question 8

Reduce colonic bacteria responsible for ammonia formation

Answer 8

Neomycin sulfate

Question 9

To manage ascites and edema

Answer 9

IV Albumin