PATH 181 LO 7 Flashcards

1
Q

what does systole mean?

A

contraction of heart

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2
Q

what does diastole mean?

A

relaxation of heart

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3
Q

What are the heart and hormone regulations?

A
  • ANH (atrial natriuretic hormone)
  • Catecholamines
  • renin/angiotensin and aldosterone
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4
Q

What is the systolic hypertension?

A

> 140 mmHg

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5
Q

What is the diastolic hypertension?

A

> 90

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6
Q

What is the normal BP?

A

120/80

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7
Q

What is primary hypertension caused by?

A

(90-95%) in cardiac disease patients with no known cause

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8
Q

What is secondary hypertension caused by?

A

caused by renal, adrenal tumors, drugs, pregnancy

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9
Q

what is atherosclerosis?

A

hardening of the arteries and most common cause of heart disease

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10
Q

what is atheromas?

A

abnormal deposits of lipids in arteries

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11
Q

What are some risk factors for atherosclerosis?

A
  • Age
  • Sex
  • Heredity
  • Smoking
  • Hyperlipidemia
  • Diabetes
  • Lifestyle
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12
Q

What are the three major lipid components found in blood?

A
  • Triglycerides
  • Cholesterol
  • Phospholipids
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13
Q

What does apolipoprotein do?

A
  • package lipids and help with solubility and metabolism

- Directs lipids to target organs and tissues

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14
Q

What does lipoproteins do?

A
  • transport lipids in the blood

- Lipid + apolipoprotein

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15
Q

What makes lipids (which are water insoluble) soluble?

A

packaged by apolipoproteins as lipoproteins

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16
Q

What do chylomicrons do?*

A

deliver lipids to hepatic and peripheral cells

17
Q

What is homocysteine?

A

a protein marker (not an enzyme)

18
Q

What does a increased homocysteine mean?

A

coronary heart disease

19
Q

What is High sensitivity CRP?

A

inflammatory protein. If high can be at risk for cardiovascular disease

20
Q

What is the treatment for MI?

A

Anticoagulant
APTT- heparin
PT - coumadin/warfarin

21
Q

When is myoglobin

  • Detected
  • Peak
  • Duration
A
  • Detected: 1-4 hrs
  • Peaks: 6-9 hrs
  • Duration: 1 day
22
Q

When is troponin

  • detected
  • peak
  • duration
A
  • detected: 4-6 hrs
  • peak: 12-48hrs
  • Duration: 7-10 days
23
Q

When is CK

  • detected
  • peak
  • Duration
A
  • detected: 4-6 hrs
  • peaks: 24 hrs
  • duration: 2-3 days
24
Q

When is AST

  • detected
  • peak
  • duration
A
  • detected: 6-8 hrs
  • peaks: 24 hrs
  • duration: 4-6 days
25
Q

When is LD

  • detected
  • peak
  • duration
A

detected: 12-24 hrs
- peaks: 48-72
- Duration: 10 days