PATH 181 correlations Flashcards

1
Q
Acute Bleed
RBC
HB
HCT
MCV
MCH
MCHC
RDW
Morphology 
ret count 
Type of anemia
A
RBC=decreased
Hb=decreased
HCT=decreased
MCV=normal
MCH=normal
MCHC=normal
RDW=normal 
Morph=normal
Ret count= increased 
Anemia=normocytic/normochromic
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2
Q
Iron Def
WBC
RBC
HB
HCT
MCV
MCH
MCHC
RDW
PLT
morph
ret count
serum iron 
TIBC
transferrin 
ferritn 
anemia
A
WBC=normal
RBC=decreased
HB=decreased
HCT=decreased
MCV=decreased
MCH=decreased
MCHC=decreased
RDW=increased
PLT=variable 
morph=hypocrhomia, micrsocytosis, ansiocytosis
ret count=normal
serum iron=decreased
TIBC=increased
Transferrin=decreased
Ferritin=decreased
Anemia=Microcytic/hypochromic
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3
Q
Megaloblastic Anemia
WBC
RBC
HCT
Hemoglobin
MCH
MCV
MCHC
RDW
ret count
morph 
neutrophils
PLT
serum iron
inconjugated bilirubin
LD
serum b12
folic acid
serum homocysteine
urine urobilinogen
urine bilirubin 
Anemia
A
WBC= normal
RBC=decreased
HCT=decreased
Hemoglobin=decreased
MCH=normal
MCV=increased
MCHC=normal
RDW=increased
ret count= decreased
morph=megaloblasts 
neutrophils=hypersegmented and enlarged
PLT=normal to decreased
serum iron=increased
unconjugated bilirubin=increased
LD=increased
Serum B12=decreased
Folic acid=decreased
Serum homocysteine=increased
urine urobilinogen=increased
urine bilrubin=negative 
Anemia=Macrocytic/normochromic
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4
Q

What type anemia is aplastic anemia?

A

normochromic/normocytic

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5
Q

What type of anemia is sickle cell anemia?

A

normocytic/normochromic

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6
Q

What type of anemia is Thalassemia?

A

microcytic/hypochromic

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7
Q

What type of anemia is hemolytic disease of newborn?

A

normocytic/normochromic

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8
Q

What type of anemia is immune hemolytic anemia?

A

normochromic/ normocytic

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9
Q
Hemochromatosis
HB
serum iron and ferriton
Transferrin saturation 
TIBC
genetic tests
A
HB-increased
serum iron and ferritin=increased
transferrin sat=increased
TIBC=decreased
gentic tests=positive
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10
Q
Mono
WBC
Lymph
RBC
platelets
LD,AST,ALT, bilirubin
heterophile antibody test 
EBV
IgM
IgG
A
WBC=decreased
Lymph=increased
RBC=normal
Platelets=normal
LD,AST,ALT, bilirubin=increased
heterophile antibody test=positive
EBV=positive
IgM=increased early
IgG=increased later
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11
Q
multiple myeloma
Blood:
Pancytopenia
ESR
anion gap
calcium
uric acid
urea,creatinine
total protein
Albumin
monoclonal immunoglobin
B2 microglobulin
Urine:
bence jones 
Albumin
Microscpoic
A
Pancytopenia=normocytic normochromic
ESR=increased
Anion gap=decreased
Calcium=increased
Uric acid=increased
Urea,creatinine=increased
Total protien=increased
Albumin=decreased
Monoclonal=increased
B2=increased
Urine;
bence jones=positive
Albumin:increased
Micrscopic: hyaline casts tubular epithelial casts
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12
Q
Hemo A and B
PT
APTT
PLT count
Bleeding time
Factor VIII
Factor IX
A
PT=normal
APTT=prolonged
PLT=normal
Bleeding time=normal
Factor 8/9= decreased
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13
Q
Von Willebrands 
PT
PTT
PLT count
PLT function
Bleeding time
A
PT=normal
PTT= normal or prolonged
PLT= normal
PLT function= variable 
Bleeding time= prolonged
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14
Q
DIC
PT
PTT
Platelets
D-Dimer
Fibrinogen
RBC
LD
inconjugated bilirubin
Free haptoglobin
A
PT=prolonged
PTT=prolonged
Platelets=decreased
D-Dimer=postive
Fibrinogen= decreased
RBC=decreased -schisocytes
LD=increased -intravascular hemolysis
unconjugated bilrubin=increased
Free haptoglobin=decreased
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15
Q
Gomerulonephritis: Nepthritic
Blood:
WBC
RBC
ESR
NA,K,Cl, HCO3
total calcium
ionized calcium 
urea creatinine
lipids
albumin
Urine:
GFR
volume
osmolality
urea/creatinine
MIcroscpoic exam:
RBC
WBC
Casts
Appearance
A
Blood:
WBC= normal increased
RBC=decreased
ESR=increased
Lytes=normal
total calcium=normal
ionized calcium=normal
Urea,creatinine=increased
lipids=normal
albumin=decreased
Urine:
GFR= decreased
volume=decreased
osmolatlity=increased
urea/creatinine=decreased
microscopic=dysmorphic
WBC=increased
Casts= RBC
appearance= murky brown
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16
Q
Gomerulonephritis: Nepthrotic 
Blood:
WBC
RBC
ESR
NA,K,Cl, HCO3
total calcium
ionized calcium 
urea creatinine
lipids
albumin
Urine:
GFR
volume
osmolality
urea/creatinine
MIcroscpoic exam:
RBC
WBC
Casts
Appearance
A
WBC=increased
RBC=decreaed
ESR=increased
lytes=normal
total calcium=normal
ionized calcium=normal
urea, creatinine=increased
lipids=increased
Albumin=decreased
urine:
GFR=decreased
volume=decreased
Protein=increased
osmolity=increased
urea/creatinine=decreased
WBC=increased
Casts=fatty casts 
Oval fat bodies
fat droplets
17
Q
Renal Tubular acidosis
Blood: 
Na, K
Cl
pH
Urine:
Na, K
pH
Microscopic
A
Blood: 
Na, K=decreased
Cl= increased
pH=decreased
Urine: 
Na,K= increased
pH=increased
microscopic= RBC, WBC, renal tubular cells
18
Q
Cystitis
Blood
Protein
Leukocyte
Nitrites
A

Blood= negative
Protein= negative
Leukocyte=postive
nitrites = positive

19
Q
Plyelonephritis
Blood
Protein
leukovyte
nitirtes
SG
A
Blood= positive
Protein=present
Leukocyte=positive
Nirtites=positive
SG=decreased
20
Q
Renal Failure
WBC
RBC
Na
K
Cl
pH
Mg
Ca
Albumin
urea,creatinine
A
WBC= increased
RBC=normal or decreased
Na=normal or decreased
K=increased
Cl=increased
pH=decreased
Mg=increased
Ca=decreased
Albumin=decreased
Urea,creatinine, uric acid=increased
21
Q
Renal Failure
GFR
Volume
Na
SG
Albumin
A
GFR decreased
Volume=decreased
Na=increased
SG=decreased
Albumin=increased
22
Q
Heart failure
WBC
RBC
Na, Cl, Protein, albumin
AST, CK, LD
GGT
pO2
pCO2
Creatine, urea
Urine Na, total volume
BNP
A
WBC=increased
RBC=increased
Na, Cl, Protein, Albumin=decrease
AST, CK,LD= increased
GGT=increased
pO2=decreased
pCO2=decreased
Creatinine, urea=increased
Urine Na, Total volume= decreased
BNP=increased
23
Q

Order of markers from forst etected to last

A

Myoglobin, troponin, CK, AST, LD

24
Q
Malabsorption
Albumin/total protein 
Calcium
Vit A,D,K,E
Prothrombin time
A

Albumin=decreased
Calcium=decreased
Vit A,D,K,E= decreased
Prothrombin time=prolonged

25
Q
GI disease 
WBC
RBC
ESR
Prothrombin time
H,Na,K,Cl
pH, CO2
Albumin
Calcium
A
WBC=shift to left
Prothrombin time=prolonged
H, Na, K, Cl= decreased
pH, CO2= increased
Albumin=decreased
Calcium=decreased
26
Q
Prehepatic
RBC
ret count
inconjugated bilirubin
Conjugated bilirubin
Total bilirubin
Urine urobilinigen 
Urine bilirubin
Albumin
LD
AST
ALT, GGT, ALP
Prothrombin time
B12, Folic acid
A
RBC=decreased
ret count= increased
Unconjugated bilirubin= increased
Conjugated biliruibin= normal
Tota; bilirubin=normal to increased
Urine urobilinogen=increased
Urine bilirubin=normal
Albumin=normal
LD=increased
AST=increased
ALT, GGT, ALP= normal
Prothrombin time=normal
B12, folic acid= decreased
27
Q
Hepatic 
RBC
WBC
Prothrombin time
Urea
Glucose
total bilirubin, Conjugated and unconjugated 
Urine urobilinogen 
Urine bilirunin
Albumin
Globulin
ALT,AST
ALP
LD
GGT
Ammonia
cholesterol
A
RBC=normal or decreased
WBC=normal to increased
Prothrombin time=prolonged
Urea=normal
Glucose=normal
Conjugated and uconjugated=increased
Urine urobilinigen=increaed 
Urine bilirubin= normal to increased
Albumin=normal to decreased
Globulin=normal to increased
ALT,AST= increased
ALP= normal
LD= increased
GGT= increased
Ammonia=normal or increased
Cholesterol=normal or deceased
28
Q
Post hepatic 
WBC
RBC
Prothrombin time
Urea
Glucose
Total bilirunbin, conjuated
unconjugated bilirubin
Urine urobilnogen 
Urine bilirubin
Albumin
Globulin
ALT,AST
ALP
LD
GGT
amylase/lipase
A
WBC=normal
RBC= normal
Prothrombin time= normal
Urea= normal
Glucose= normal
Total bilirubin, conjugated= increased
Unconjugated= normal or increased
Urine urobilinogen=decreased
Urine bilinogen= increased
Albumin=normal
Globulin=normal
ALT, AST= normal
ALP=increased
LD=normal
GGT= increased
Amylase/lipase= increased if pancreas
29
Q
Pancreatitis
WBC
ESR
Amylase
urine amylase
Lipase
Calcium
Mg
GGT, AST, LD
ALT
ALP
T bilirubin
A
WBC= increased
ESR= incrreased
Amylase= increased
Urine amylase= increased
Lipase= increased
Calcium= increased or decreased
Mg= decreased
GGT, AST, LD= increased
ALT= normal
ALP= normal
T bilirubin