Part 3: Introduction to muscular tissue Flashcards
3 types of muscle tissue + (moves ___)
- Skeletal – moves body
- Cardiac – moves blood
- Smooth – moves food, liquid, air
muscle cells are ____
Specialized cells with contractile & conducting properties
muscle tissue provides ability to ____
1) move
2) regulate organ volumes
3) maintain posture
4) communicate
5) produce body heat
4 properties of muscle tissue
Excitability: ability to respond to stimulation (e.g., nerves, hormones)
Contractility: ability to shorten in response to an action potential
Extensibility: ability to contract over different lengths (range – without injury)
Elasticity: ability to regain original length after contraction
Major characteristics of skeletal muscle
1) somatic structures (under voluntary control though not always conscious)
2) innervated by spinal nerves & cranial nerves
3) contractile organs (long fibres that contract along longitudinal axis) that attach directly or indirectly onto bones
4) Their contractions produce motion of the body
Major functions of skeletal muscle
1) Produce movement at various joints of the skeleton
2) Maintain posture & body position (even at rest)
3) Support soft tissues
4) Regulate entering & exiting of material (sphincters in digestive & urinary systems)
5) Maintain body temperature
6) Communication (verbal & non-verbal expressions)
A skeletal muscle is surrounded by _____ (becomes continuous with ____)
an epimysium
periosteum
Muscle belly is composed of _______
bundles of muscle fascicles
A muscle fascicle is surrounded by ______ which does what?
an perimysium
protect from damage, contains capillaries & nerve fibres)
Each fascicle is composed of _______
bundles of muscle fibres (muscle cells)
A muscle fibre is surrounded by _______. Each fibre is composed of ______
an endomysium
bundles of myofibrils
Each myofibril is composed of _______
bundles of myofilaments (proteins responsible for muscle contraction)
Label
(left) Epimysium
Muscle fascicle
Endomysium
Perimysium
(right) Nerve
Muscle fibres
Blood vessels
Label
Perimysium
Muscle fibre
Endomysium
Label
(left) Mitochondria
Sarcolemma
Myofibril
Axon
Sarcoplasm
(right) Capillary
Endomysium
Myosatellite cell
Nucleus
sacrolemma (def.)
cell membrane of muscle fibre
sacroplasma (def.)
cytoplasm in muscle cell
Muscle fibres develop through the fusion of cells called _____
myoblasts
Myosatellite cells are ____
Only stem cells that remain; repair damaged muscle tissue
Muscle fibre length
40 cm
Myofibril (def.)
Contractile element composed of myofilaments (protein that exhibit striations)
Thin filament (def.)
actin
Thick filament (def.)
myosin
Mitochondrial activity + chemical breakdown of glycogen =
ATP power for muscle contraction
Myoglobin contains ____
stored oxygen
Sarcoplasmic reticulum stores _____
Ca2+ to promote muscle contraction
Transverse tubule conducts _____
electrical impulses (action potential) for muscle fibre contraction
_____is the basic contractile unit of a muscle (~ 10 000 per myofibril)
Sarcomere
Boundaries of a sarcomere are a _____
pair of Z-lines (protein discs repeated along myofibril)
Centre of a sarcomere is _____
an M-Line (middle – stabilize position of myosin)
elastic protein that connects myosin to Z lines
Titin
Label
top: titin
bottom (l to r): Z-line , M-line, Z-line
H-band contains ______
thick filaments only
I-band: (isotropic – light – uniform in each direction) contains ____
thin filaments only
A-band: (anisotropic – dark – directionally dependent) contains _____
both thin & thick filaments
Zone of overlap is where?
striations & where calcium ions are released
Label
top: I-band, H-band, I-band
bottom: A-band
Sliding Filament Theory contraction effects.
1) Actin slide toward each other
2) Width of the I-band & H-band decreases
3) Zone of overlap gets larger
4) Z lines move closer together
5) Width of the A-band remains constant
Sliding Filament Theory descr.
Cross-bridging between thick & thin filament ;Triggered by presence of calcium ions ; Requires ATP
nerve stimulating muscle steps
1) Muscle cells (fibres) are innervated by somatic motor neurons they penetrates epimysium, then perimysium, & ends at a muscle fibre through the endomysium.
2) Axon terminal at the tip of neuromuscular junction (NMJ) where it releases acetylcholine - Ach
3) signals the muscle cell to contract
4) Contraction is an all or none phenomenon
Steps That Initiate a Muscle Contraction
1) ACh released, binding to receptors in sarcolemma
2) Action potential reaches T tubule
3) Sarcoplasmic reticulum releases Ca2+
4) Active site exposure and cross-bridge
formation
5)Contraction Begins (power stroke)