Parkinson's Disease Flashcards
What characterizes Parkinson’s disease.
Clinical condition is characterized by gradual slowing a voluntary movement (bradykinesia); muscular rigidity; stupid posture; distinctive gate with short, accelerating steps; managed facial expression; and resting tremor.
What is Parkinson’s disease
It is a degeneration of the substantia nigra in the basal ganglia of the midbrain, which leads to depletion of the neurotransmitter dopamine. Dopamine is normally produced and stored in the substantia nigra and promotes smooth, purposeful movements and modulation of motor function. Depletion of dopamine leads to impairment of the extrapyramidal tracks and consequent loss of movement coordination
What percentage of DA neurons are lost before the patient begins to have the motor signs of Parkinson’s disease
80%
The majority of all cases of classic Parkinson’s disease are what
Primary, or idiopathic, and secondary
What is secondary or iatrogenic Parkinson’s disease
Is drug or chemical related (dopamine)
His Parkinson’s a genetic disease
Yes
In Parkinson’s disease, what are some complications that can occur
Injuries from Falls, skin breakdown from immobility, and urinary tract infections
Death is usually caused by what in patients that have Parkinson’s disease
Aspiration pneumonia or other infections
What is juvenile parkinsonism
It’s associated and people younger than age 40 who have Wilson’s disease, progressive lenticular degeneration, or Huntington’s disease.
Which gender does Parkinson’s disease affect more
Men slightly more often than it does want to
What race has a higher incidence of Parkinson’s disease
Hispanics/Latinos and whites
Parkinson’s disease progresses through stages what is the first stage
Mild unilateral dysfunction
What is the second stage Parkinson’s disease
Mild bilateral dysfunction, as evidenced by expressionless face and gait changes
What is the third stage of Parkinson’s disease
Increasing dysfunction, with difficulties in walking, initiating movements, and maintaining equilibrium
What is the fourth stage of Parkinson’s disease
Severe disability, including difficulties in walking in maintaining balance and steady propulsion, Rigidity, and slow to movement.