Obesity I Flashcards
What is the technical definition of obesity?
Excess body fat
BMI >30
True or false: OA is a risk factor of obesity
True
True or false: gallstones and renal stones are risk factors of obesity
not renal stones, but gall stones yes.
True or false: GYN abnormalities are risk factors of obesity
True
How large a role are genetics in obesity?
Small
How does polycystic ovarian syndrome lead to obesity?
Too much insulin is being produced, and does not function normally
How does hypothyroidism lead to obesity?
Decrease in thyroid hormone
How does Cushing’s syndrome lead to obesity?
Adrenal glands overproduce cortisol
What are the meds that lead to weight gain? (5)
Antipsychotics Antidepressants DM meds Antiepileptic Glucocorticoids
What is the adaptive viewpoint of fat and evolution?
Accumulation of fat was advantageous
What are “thrifty genes”?
Theoretical genes that caused increased fat deposition, due to common famine
What is the maladaptive viewpoint of obesity?
Obesity has never been advantageous–some do not have brown adipose tissue
What is the neutral viewpoint of obesity?
Obesity never advantageous.
Many genes involved in weight regulation
What is the set point theory?
Upper and lower points exist, but upper point increased
What are the three key players in energy homeostasis?
Brain
GI tract
Adipose tissue