Neurological Conditions Flashcards
risk factors for infection
immunosuppression drug regimens
meningitis
- defintion
inflammation of the meninges that cover and protect the brain and spinal cord
meningitis
- types
bacterial
viral
fungal
meningitis
- classic triad
fever
headache
nuchal rigidity
what is nuchal rigidity
tightness and soreness of neck
meningitis
- other s/s
photophobia
kernigs
brudzinski
hemiparesis
altered LOC
cranial nerve palsies
petechial rash
kernigs sign
knee flexion and cannot straighten
brudzinskis sign
neck flexed and knees come in
meningitis
- bedside risk score
unfavorable outcome correlates with
- increased age
- HR >120
- postive gram stain 1 hour after presentation
- cranial nerve palsy
- decreased GCS
meningitis
- lumbar puncture
opening pressure is increased
leukocyte could is elevated
protein is elevated
meningitis
- prevention
meningococcal vaccination
meningitis
- priority for bacterial
antibiotics early administration
meningitis
- other meds we can give
antipyretic
antiseizure
IVF
steroids (controversial)
meningitis
- treatment is __________ and directed at __________ management
supportive, symptom
meningitis
- consult
epidemology
infection control
meningitis
- monitor
vital signs, respiratory status, neuro (safety)
meningitis
- why are we cautious about pain meds
we still need to do an accurate mental status exam
brain abscess
- most common in
immunocompromised
brain abscess
- how to get it
extended infection of ear, mastoid, or sinuses
metastasis from another site
brain abscess
- intracranial (brain) absecess ss
progressive symptoms
headache worse in morning
reduced vision
seizures
altered LOC
brain abscess
- intracranial epidural abscess s/s
nuchal rigidity
drainage from sinus or ears
brain abscess
- clinical presentation of frontal lobe
hemiparesis
expressive aphasia
seizures
frontal headache
brain abscess
- clinical presentation of temporal lobe
localized headache
changes in vision
facial weakness
receptive aphasia
brain abscess
- clinical presentation of cerebellar
occipital headache
ataxia
nystagmus
brain abscess
- labs
increase WBC
elevated erythrocyte sedimentation rate
blood cultures
brain abscess
- lumbar puncture
elevated opening pressure
increased protein levels
increased lympocytes
brain abscess
- what do we need to initiate asap
antibiotics
brain abscess
- monitor
VS, RR, neuro
brain abscess
- meds ot administer besides antibiotics
antipyretic therpy
analgesics
brain abscess
- coordinate with
home health care for long term antibiotic therapy
encephalitis
- defintion
acute inflmmatory process of the brain tissue
viral infections
encephalitis
- manifestations
flaccid paralysis
Parkinson like movement
headache
fever
confusion
changes in LOC
vector borne rash
encephalitis
- medication
acyclovir for HSV infection
amphotericin for anti fungal
encephalitis
- medication key
early administration
encephalitis
- what assessment is frequent
neuro
encephalitis
- supportive care consists of
pain meds
seizure prevention
injury prevention
patient safety
multiple sclerosis
- defintion
immune mediated demyelinating disease of the central nervous system
multiple sclerosis
- disease progression
replaces and remissions
slow steady progressive dysfunction
multiple sclerosis
- MRI results
disruption of blood brain barrier
inflammation
plaques
axonal loss
brain atrophy
multiple sclerosis
- how to get plaques
dead axons
multiple sclerosis
- same in every patient
no
multiple sclerosis
- prediction of disease
no
multiple sclerosis
- relapsing and remitting course
residual deficits may occur
multiple sclerosis
- s/s
- motor
weakness
spasticity
loss of coordination
multiple sclerosis
- s/s sensory
numbness, tingling
lhermittes sign
Lhermittes sign
numbers tingling down arm
multiple sclerosis
- s/sbrain stem
nystagmus
dysphagia
multiple sclerosis
- s/s cerebellar
gait ataxia
loss of balance
multiple sclerosis
- promenint symptom
cognitive changes
fatigue!
multiple sclerosis
- labs in CSF
banding
multiple sclerosis
- cure
none
multiple sclerosis
- medications are used to
treat relapses
multiple sclerosis
- relapse management
steroids
multiple sclerosis
- immune suppressants
immunomodulating disease-modifitying agents
immunosupporesive therapy
multiple sclerosis
- symptom management for spasticity
baclofen
benzes (valium/dantrolene)
multiple sclerosis
- symptom management for ataxia
betablocker (inderol)
antiseizure meds (neurotin, klonapin
multiple sclerosis
- intervention about fatigue
avoid overheating
PT/OT
exercise to the point of fatigue and stop
multiple sclerosis
- assess sequelae of spasticity
difficulty with gait/sitting
hygiene
energy levels
sexual activity
multiple sclerosis
- education
mobility/transfers/safety
use of assistive devices
myasthenia gravis
- defintion
autoimmune disorder in which normal transmission of nerve impulses is interrupted at the neuromuscular junction
myasthenia gravis
- affects
voluntary muscle groups
myasthenia gravis
- result
muscle is not able to fully contract
(acetylcholine)
myasthenia gravis
- ocular MG
weakness of the eye and lid muscles only
myasthenia gravis
- bulbar MG
involves breathing, swallowing (dysphagia), and speech (dysphonia)
myasthenia gravis
- when impacting the intercostal muscles or shoulder girdle, what should me monitor
vital capaticty
respiratory
what is vital capacity
amount of air moved in and out within one breath
myasthenia gravis
- mRI
thymus gland
myasthenia gravis
- medical management used
anti cholinesterase inhibitors
seroids
immunosuppressants
myasthenia gravis
- anticholinesterase
mestinon
myasthenia gravis
- important factors of mestinon
has to be given same time every day
usually 3-4 times away
timed around when patient is most active
myasthenia gravis
- immunosuppressants risk
atypical infections
myasthenia gravis
- when on immunosuppressants will they have normal s/s of infection
no
myasthenia gravis
- plasma/IVIG what drives giving it
the response
if not responding then we won’t do it
myasthenia gravis
- plasma/IVIG duration
short
myasthenia gravis
- plasma/IVIG can be given during crisis
yes
myasthenia gravis
- nursing interventions
respirations
dysphagia
dysarthria
monitor for myasthenia crisis
myasthenia gravis
- cure
no
complications of MG
cholinergic crisis
myasthenic crisis
myasthenic crisis
- cause
under medications or lack of response to treatment
myasthenic crisis
- s/s
increased weakness
severe ocular/bulbar symptoms
failure of respiratory muscles to maintain ventilation
myasthenic crisis
- priority interventions
airway management typically through intubation
myasthenic crisis
- meds given
IVIG
sterouds
plasma
cholinergic crisis
- cause
too much acetylcholine
cholinergic crisis
- treatment
withhold medications
Guillain- barre syndrome
- definition
acute autoimmune attack on the peripheral nerve myelin, result is an acute rapid inflammatory demyelinating polyneuropathy
Guillain- barre syndrome
- weakness type
ascending
Guillain- barre syndrome
- s/s
dyskinesia
paresthesias
hyporeflexia
Guillain- barre syndrome
- autoimmune?
yes
Guillain- barre syndrome
- hallmark sign
inflammatory lesions throughout the peripheral nervous system
Guillain- barre syndrome
- what attack the normal myelin
macrophages
Guillain- barre syndrome
- s/s
ascending weakness
begins in legs and progress upwards
Guillain- barre syndrome
- complications
ineffective ventilation if diaphragm and respiratory muscles are impacted
Guillain- barre syndrome
- peak severity in ___ weeks
2
Guillain- barre syndrome
- autonomic dysfunction
vagus nerve
- orthostatic hypo- hypert
- cardiac arrhythmias/instability
Guillain- barre syndrome
- weakness usually preceded by
paresthesias (numbers and tingling)
Guillain- barre syndrome
- lumbar puncture results
shows increased protein in CSF
Guillain- barre syndrome
- pulmonary function tests
vital capacity and negative inspiratory force
Guillain- barre syndrome
- what conversation is had with the patient upon admission
elective intubation
Guillain- barre syndrome
- medication
plasma/IVIG (response determines frequency)
Guillain- barre syndrome
- monitor hemodynamic compromise
ECG
BP
fluid status
Guillain- barre syndrome
- monitor
VS
lung sounds
ABG
vital capacity
negative inspiratory force
neuro status
CN involmenet
increase weakness
Guillain- barre syndrome
- complications
respiratory failure
DVT