Hematology and Immunology Neutropenia and Bleeding Disorders Flashcards

1
Q

medications that alter platelets

A

antihypertensives
penicillin
sulfa containing meds
aspirin based
NSAIDs

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2
Q

neutropenia
- defintion

A

decreased production or increased destruction of neutrophils

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3
Q

neutropenia
- risk

A

infection is biggest risk

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4
Q

neutropenia
- s/s of infection

A

not have the same response to infection
EX: might not always have a temp

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5
Q

neutropenia
- medical management

A

treatment depends on the cause

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6
Q

neutropenia
- precautions

A

reversal isolation
no flowers/fruit
private room
nurse wears mask/gloves
good hand hygiene
avoid crowded areas

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7
Q

thrombocytopenia
- variety of factors

A

decreased production in the bone marrow
increased destruction
increased consumption

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8
Q

thrombocytopenia
- clinical manifesations

A

increased risk of bleeding

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9
Q

thrombocytopenia
- patient safety and education

A

bleeding
no aspirin/antiplatelet

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10
Q

hemophilia
- what is it

A

inherited bleeding disorder
missing factor 8

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11
Q

hemophilia
- clinical manifesations

A

hemorrhages into various parts of the body
- joints
- head

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12
Q

hemophilia
- risk

A

bleeding and falls

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13
Q

hemophilia
- medical and nursing management

A

recumbent forms of factor 8 when patient actively bleeding or used prophylactically

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14
Q

hemophilia
- medications or foods to avoid

A

avoid NSAIDs, general supplements, alcohol

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15
Q

DIC
- definiton

A

altered hemostasis mechanism causes massive clotting in microcirculation, as clotting factors are consumed, bleeding occurs

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16
Q

DIC
- symptoms related to

A

tissue ischemia and bleeding

17
Q

DIC
- triggers

A

sepsis
trauma
shock
cancer
abrupto placenta
toxins
allergic reactions

18
Q

DIC
- treatment

A

underlying causes
correct tissue ischemia
replace fluids and electrolytes
maintain blood pressure
replace coagulation factors

19
Q

DIC
- med

A

heparin
- stop bleeding

20
Q

DIC
- how do we replace coagulation factors

A

PRBC
FFP
platelets

21
Q

DIC
- complication

A

organ failures

22
Q

DIC
- platelet count

23
Q

DIC
- PT

24
Q

DIC
- aPTT

25
DIC - thrombin time
high
26
DIC - fibrinogen
low
27
DIC - d-dimer
high
28
DIC - fibrin degradation products
high
29
unfrac heparin - test
aPTT
30
unfrac heparin - aPTT therapeutic
1.5-2.5 times control (~37-87)
31
unfrac heparin - complication
heparin induced thrombocytopenia
32
heparin - reversal
protamine sulfate
33
warfarin - test
INR
34
warfarin - INR therapeutic
2-3
35
warfarin - reversal
vit K
36