Neoplasm: Disorders Of Cell Growth

Question 1

Hypertrophy?

Answer 1

Pathological or physiological increase in cell size

Question 2

Hyperplasia?

Answer 2

Increase in number or cells

Question 3

Atrophy?

Answer 3

Decrease in number of cells

Question 4

Metaplasia?

Answer 4

Change in formation, one fully differentiate cell type changing into another fully differentiated cell type

Question 5

Tumour?

Answer 5

Swelling

Question 6

Neoplasia?

Answer 6

An abnormal growth of tissue

It persists even after cessation of the stimuli

Due to uncoordinated proliferation

Question 7

Benign neoplasm?

Answer 7

A neoplasm that does not invade or metastasise

Question 8

Carcinoma?

Answer 8

Cancer if epithelial cells

Question 9

Sarcoma?

Answer 9

Malignant connective tissue tumour

E.g. osteosarcoma

Question 10

Leukemia?

Answer 10

Malignant blood

Not typically mass forming

Question 11

Lymphoma?

Answer 11

Malignant tumour of lymphoid cells

Question 12

Seminoma?

Answer 12

Arise from germ cells in the testes

Question 13

Melanoma?

Answer 13

Malignant tumour if melanocytes in the skin

Question 14

Are all neoplasms tumours?

Answer 14

Yes

Question 15

choristoma?

Answer 15

Abnormal growth of normal tissue structures and an unusual site

Question 16

Is a benign tumour smooth or iregukar?

Answer 16

Smooth

Question 17

What is a benign tumour confined to?

Answer 17

Basement membrane

Question 18

Is a malignant tumour poorly or well differentiated?

Answer 18

Poorly differentiated

Question 19

Benign or malignant?

Answer 19

Malignant

Question 20

Adenocarcinoma?

Answer 20

Tumour of glands

Question 21

Behavior of cancer cells?

Answer 21

Unregulated growth
Loss of cohesion
immaturity
immortality

Question 22

Dysplasia?

Answer 22

Bad/disordered formation

Question 23

Mild, moderate and severe dysplasia?

Answer 23

Mild bottom third

Moderate = 2/3

Severe all layers

Question 24

What is the most common type of tumour?

Answer 24

Carcinoma

Question 25

Necrosis?

Answer 25

Premature /unregulated cell death

Question 26

Metastasis?

Answer 26

Movement if tumour Via blood vessels or lymphatics

Question 27

Genes common to a lot of cancers?

Answer 27

EGFR Ras RAF P53

Question 28

Oncogenes?

Answer 28

EGFR Ras Raf

Question 29

Proto-oncogene to oncogene?

Answer 29

Proto-oncogene - before the gene has mutated to be promote cancer

Question 30

Clinical manifestations of cancer?

Answer 30

Pain Loss of function Hamemorrhage (cough up blood)

Question 31

What are distant manifestations of cancer?

Answer 31

DVT Paraneoplastic syndrome Cachexia

Question 32

Atrophy refers to?

Answer 32

A pathological and physical logical decrease in the number or size of cells

Question 33

Name a benign neoplasm?

Answer 33

Adenoma

Question 34

A high grade tumour … ?

Answer 34

Is usually highly mitotically active

Question 35

Answer 35

Routine testing for HPV in all oral SCC is recommended Few oral tumours are caused by HPV