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BDS2.5 Applied Biomedical Sciences > Neoplasm: Disorders Of Cell Growth > Flashcards

Neoplasm: Disorders Of Cell Growth Flashcards

1
Q

Hypertrophy?

A

Pathological or physiological increase in cell size

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2
Q

Hyperplasia?

A

Increase in number or cells

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3
Q

Atrophy?

A

Decrease in number of cells

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4
Q

Metaplasia?

A

Change in formation, one fully differentiate cell type changing into another fully differentiated cell type

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5
Q

Tumour?

A

Swelling

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6
Q

Neoplasia?

A

An abnormal growth of tissue

It persists even after cessation of the stimuli

Due to uncoordinated proliferation

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7
Q

Benign neoplasm?

A

A neoplasm that does not invade or metastasise

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8
Q

Carcinoma?

A

Cancer if epithelial cells

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9
Q

Sarcoma?

A

Malignant connective tissue tumour

E.g. osteosarcoma

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10
Q

Leukemia?

A

Malignant blood

Not typically mass forming

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11
Q

Lymphoma?

A

Malignant tumour of lymphoid cells

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12
Q

Seminoma?

A

Arise from germ cells in the testes

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13
Q

Melanoma?

A

Malignant tumour if melanocytes in the skin

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14
Q

Are all neoplasms tumours?

A

Yes

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15
Q

choristoma?

A

Abnormal growth of normal tissue structures and an unusual site

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16
Q

Is a benign tumour smooth or iregukar?

17
Q

What is a benign tumour confined to?

A

Basement membrane

18
Q

Is a malignant tumour poorly or well differentiated?

A

Poorly differentiated

19
Q

Benign or malignant?

20
Q

Adenocarcinoma?

A

Tumour of glands

21
Q

Behavior of cancer cells?

A

Unregulated growth
Loss of cohesion
immaturity
immortality

22
Q

Dysplasia?

A

Bad/disordered formation

23
Q

Mild, moderate and severe dysplasia?

A

Mild bottom third

Moderate = 2/3

Severe all layers

24
Q

What is the most common type of tumour?

25
Q

Necrosis?

A

Premature /unregulated cell death

26
Q

Metastasis?

A

Movement if tumour

Via blood vessels or lymphatics

27
Q

Genes common to a lot of cancers?

A

EGFR

Ras
RAF
P53

28
Q

Oncogenes?

A

EGFR
Ras
Raf

29
Q

Proto-oncogene to oncogene?

A

Proto-oncogene - before the gene has mutated to be promote cancer

30
Q

Clinical manifestations of cancer?

A

Pain
Loss of function
Hamemorrhage (cough up blood)

31
Q

What are distant manifestations of cancer?

A

DVT
Paraneoplastic syndrome
Cachexia

32
Q

Atrophy refers to?

A

A pathological and physical logical decrease in the number or size of cells

33
Q

Name a benign neoplasm?

34
Q

A high grade tumour … ?

A

Is usually highly mitotically active

35
Q
A

Routine testing for HPV in all oral SCC is recommended

Few oral tumours are caused by HPV

BDS2.5 Applied Biomedical Sciences (48 decks)

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