Mycology EC

Question 1

Histoplasmosis

Answer 1

Mississippi/Ohio river valley (South/midwest)

Histo Hides in macrophages

Question 2

Blastomycosis

Answer 2

Mississippi river/great lakes

Blasto with Broad Based Buds

Inflammatory lung disease (bone/skin dissemination)

Question 3

Coccidiodomycosis

Answer 3

Southwestern US

Pneumonia/Meningitis (disseminate to bone and skin)

Question 4

Paracoccidiodomycosis

Answer 4

“Paracoccidio parasails with the CAPTIANS WHEEL all the way to LATIN AMERICA”

budding yeast with captain’s wheel formation

Question 5

Tinea versicolor

Answer 5

Caused by Malassezia furfur

Degradation of lipids produces acids that damage melanocytes
Hypo/Hyperpigmentation

“Spaghetti and meatball” appearance

Question 6

Microsporum, Trichophyton, Epidermophyton

Answer 6

Dermatophytes

Tinea pedis (foot)
Tinea cruris (groin)
Tinea corporis (ringworm on body)
Tinea capitis (head)
Tinea unguium (fingernails)

Question 7

Candida albicans

Answer 7

Opportunistic

Oral/Esophageal thrush
Vulvovaginitis
Diaper rash
Endocarditis (IV drug users)

Question 8

Aspergillus fumagatus

Answer 8

Invasive aspergillosis: AIDS and chronic granulomatous disease

Allergic bronchopulmonary aspergillosis: asthma or CF

Aspergillomas: TB infection

Aflatoxins can cause HCC

Question 9

Cryptococcus neoformans

Answer 9

Pigeon droppings

cryptococcal meningitis

“Soap bubble” brain lesions

Question 10

Mucor and Rhizopus

Answer 10

Ketoacidotic diabetic and leukemic patients

Proliferate in blood vessels, penetrate cribriform plate, and enter brain/eye

Headache, facial pain, black necrotic eschar on face

Question 11

Pneumocystis jirovecii

Answer 11

Diffuse interstitial pneumonia in AIDS patients with a CD4<200

Question 12

Sporothrix schenckii

Answer 12

“Rose gardener’s disease”

Lives on thorn, local pustule/ulcer in skin with nodules along draining lymphatics