Drug Reactions EC

Question 1

Drugs causing Coronary vasospasm

Answer 1

Cocaine
Sumatriptan
Ergot alkaloids

Question 2

Drugs causing Cutaneous flushing

Answer 2

Vancomycin
Adenosine
Niacin
Ca blockers

“VANC”

Question 3

Drugs causing Dilated cardiomyopathy

Answer 3

Doxorubicin

Daunorubicin

Question 4

Drugs causing Torsades de pointes

Answer 4

Class III (sotalol) antiarrhythmics
Class IA (quinidine) antiarrhythmics
Macrolides
Antipsychotics
TCAs

Question 5

Drugs causing Agranulocytosis

Answer 5

Clozapine
Carbamazepine
Colchicine
Propylthiouracil
Methimazole
Dapsone

“Agranulocytosis Could Certainly Cause Pretty Major Damage”

Question 6

Drugs causing Aplastic anemia

Answer 6

Carbamazepine
Methimazole
NSAIDs
Benzene
Chloramphenicol
PTU

“Can’t Make New Blood Cells Properly”

Question 7

Drugs causing Direct Coombs-positive hemolytic anemia

Answer 7

Methyldopa

Penicillin

Question 8

Drug causing Gray baby syndrome

Answer 8

Chloramphenicol

Question 9

Drugs causing Hemolysis in G6PD deficiency

Answer 9

Isoniazid
Sulfonamides
Dapsone
Primaquine
Aspirin
Ibuprofen
Nitrofurantoin

“hemolysis IS D PAIN”

Question 10

Drugs causing MegaloBLASTic anemia

Answer 10

Phenytoin
Methotrexate
Sulfa

“having a BLAST with PMS”

Question 11

Drug causing Thrombotic complications

Answer 11

OCP’s

Question 12

Drugs causing Cough

Answer 12

ACE inhibitors

Question 13

Drugs causing Pulmonary fibrosis

Answer 13

Bleomycin
Amiodarone
Busulfan
Methotrexate

“Breathing Air Badly from Medications”

Question 14

Drug causing Acute cholestatic hepatitis, jaundice

Answer 14

Erythromycin

Question 15

Drugs causing Focal to massive hepatic necrosis

Answer 15

Halothane
Amanita phalloides (deathcap mushroom)
Valproic acid
ACetaminophen

“liver HAVAc”

Question 16

Drug causing Hepatitis

Answer 16

INH

Question 17

Drugs causing Pseudomembranous colitis

Answer 17

Clindamycin

Ampicillin

Question 18

Drugs causing Adrenocortical insufficiency

Answer 18

Glucocorticoid withdrawal

Question 19

Drugs causing Gynecomastia

Answer 19

Spironolactone
Digitalis
Cimetidine
Alcohol
Ketoconazole

“Some Drugs Create Awkward Knockers”

Question 20

Drugs causing Hot flashes

Answer 20

Tamoxifen

Clomiphene

Question 21

Drugs causing Hyperglycemia

Answer 21

Tacrolimus
Protease inhibitors
Niacin
HCTZ
Beta-blockers
Corticosteroids

“Taking Pills Necessitates Having Blood Checked”

Question 22

Drugs causing Hypothyroidism

Answer 22

Lithium
Amiodarone
Sulfonamides

Question 23

Drugs causing Fat redistrobution

Answer 23

Glucocorticoids

Protease inhibitors

Question 24

Drugs causing Gingival hyperplasia

Answer 24

Phenytoin
Verapamil
Cyclosporine
Nifedipine

Question 25

Drugs causing Gout

Answer 25

``` Pyrazinamide Thiazides Furosemide Niacin Cyclosporin ``` "Painful Tophi and Feet Need Care"

Question 26

Drugs causing Myopathies

Answer 26

``` Fibrates Niacin Colchicine Hydroxychloroquine Interferon-alpha Penicillamine Statins Glucocorticoids ``` "Fish N CHIPS Give you myopathies"

Question 27

Drugs causing Osteoporosis

Answer 27

Corticosteroids | Heparin

Question 28

Drugs causing Photosensitivity

Answer 28

Sulfonamides Amiodarone Tetracycline "SAT for a photo"

Question 29

Drugs causing Rash (Stevens-Johnson syndrome)

Answer 29

``` Penicillin Ethosuximide Carbamazepine Sulfa drugs Lamotrigine Allopurinol Phenytoin Phenobarbital ``` "bad rash after PEC SLAPP"

Question 30

Drugs causing SLE-like syndrome

Answer 30

``` Sulfa Drugs Hydralazine Isoniazid Procainamide Phenytoin Etanercept ``` "SHIPP-E"

Question 31

Drug causing Teeth discoloration in kids

Answer 31

Tetracyclines

Question 32

Drugs causing Tendonitis, tendon rupture, and cartilage damage

Answer 32

Fluoroquinolones

Question 33

Drugs causing Diabetes insipidus

Answer 33

Lithium | Demeclocycline

Question 34

Drugs causing Fanconi's syndrome

Answer 34

Expired tetracycline

Question 35

Drugs causing Hemorrhagic cystitis

Answer 35

Cyclophosphamide | Ifosfamide

Question 36

Drugs causing Interstitial nephritis

Answer 36

Methicillin NSAIDS Furosemide

Question 37

Drugs causing SIADH

Answer 37

Carbamazepine Cyclophosphamide SSRIs "Can't Concentrate Serum Sodium"

Question 38

Drugs causing Cinchonism (flushed, tinnitus, dizziness, impaired hearing/vision, headache, abdominal pain, N/V, diarrhea)

Answer 38

Quinidine (1A anti-arrhythmic) | Quinine (malaria)

Question 39

Drugs causing Parkinson-like syndrome

Answer 39

Antipsychotics Reserpine Metoclopramide "ARM"

Question 40

Drugs causing Seizures

Answer 40

``` Isoniazid Bupropion Imipenem Tramadol Enflurane Metoclopramide ``` "with seizures, I BITE My tongue"

Question 41

Drugs causing Tardive dyskinesia

Answer 41

Antipsychotics

Question 42

Drugs causing Antimuscarinic

Answer 42

Atropine TCAs H1 blockers Neuroleptics

Question 43

Drugs causing Disulfiram-like reaction

Answer 43

Metronidazole Cephalosporins Procarbazine 1st generation sulfonylureas

Question 44

Drugs causing Nephrotoxicity/ototoxicity

Answer 44

Aminoglycosides Vancomycin Loop diuretics Cisplatin

Question 45

P450 inducers

Answer 45

``` Chronic alcohol Modafinil St. John's Wort Phenytoin Phenobarbital Nevirapine Rifampin Griseofulvin Carbamazepine ``` "Chronic alcoholic Mona Steals Phen-Phen and Never Refuses Greasy Carbs"

Question 46

P450 inhibitors

Answer 46

``` Macrolides Amiodarone Grapefruit juice Isoniazid Cimetidine Ritonavir Acute alcohol abuse Ciprofloxacin Ketoconazole Sulfonamides Gemfibrozil Quinidine ``` "MAGIC RACKS in GQ"

Question 47

P450 substrates

Answer 47

``` Antiepileptics Antidepressants Antipsychotics Anesthetics Theophylline Warfarin Statins OCPs ``` "Always, Always, Always, Always Think When Starting Others"

Question 48

Drugs causing Pancreatitis

Answer 48

``` Didanosine Corticosteroids Alcohol Valproic acid Azathioprine Diuretics ``` "Drugs Causing A Violent Abdominal Distress"

Question 49

What are the sulfa drugs?

Answer 49

``` Probenecid Furosemide Acetazolamide Celecoxib Thiazides Sulfonamides Sulfasalazine Sulfonylureas ``` "Popular FACTSSS"