Autoantibodies and Disorders EC Flashcards

1
Q

Anti-nuclear antibodies (ANA)

A

SLE

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2
Q

Anti-dsDNA, anti-Smith

A

SLE

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3
Q

Anti-histone

A

Drug induced lupus

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4
Q

Rheumatoid factor, anti-CCP

A

Rheumatoid arthritis

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5
Q

Anti-centromere

A

CREST scleroderma

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6
Q

Anti-Scl-70 (anti-DNA topoisomerase I)

A

Diffuse scleroderma

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7
Q

Anti-mitochondrial (AMA)

A

Primary biliary cirrhosis

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8
Q

IgA anti-endomysial

IgA anti-tissue transglutaminase

A

Celiac disease

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9
Q

Anti-basement membrane

A

Goodpasture’s syndrome

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10
Q

Anti-desmoglein

A

Pemphigus vulgaris

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11
Q

Anti-microsomal

Anti-thyroglobulin

A

Hashimoto’s thyroiditis

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12
Q

Anti-Jo-1
Anti-SRP
Anti-Mi-2

A

Polymyositis

Dermatomyositis

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13
Q

Anti-SSA (anti-Ro)

Anti-SSB (anti-La)

A

Sjogren’s syndrome

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14
Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed connective tissue disease

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15
Q

Anti-smooth muscle

A

Autoimmune hepatitis

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16
Q

Anti-glutamate decarboxylase

A

Type 1 Diabetes Mellitus

17
Q

c-ACNA

A

Wegener’s (granulomatosis with polyangiitis)

18
Q

p-ANCA

A

Microscopic polyangiitis

Churg-Strauss syndrome