Module 9 Part 2 Pyelonephritis

Question 1

What is pyelonephritis and how is its treatment determined?

Answer 1

Pyelonephritis is a kidney infection and treatment depends on severity and complications.

Question 2

What are the first-line treatment options for mild, uncomplicated pyelonephritis without obstruction?

Answer 2

TMPSMX Trimethoprim Norfloxacin Ciprofloxacin or Levofloxacin.

Question 3

When might Amoxicillin/Clavulanate be used for mild pyelonephritis?

Answer 3

Amoxicillin Clavulanate might be used as a second-line option, especially when local resistance is anticipated.

Question 4

What is the recommended treatment for severe pyelonephritis, and when is it appropriate to switch to oral therapy?

Answer 4

First-line treatment includes Gentamicin with or without Ampicillin. Switch to oral therapy after 3-4 days when clinically appropriate and culture results are available.

Question 5

How is complicated pyelonephritis treated and what should be done if there is no clinical improvement after 72 hours?

Answer 5

Specific treatment is required based on the patient’s condition. If there’s no improvement, investigation for complications or urinary obstruction should be considered.