Metabolic alkalosis Flashcards

1
Q

Requires what

A

Initiation and maintenance phase

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2
Q

Small animal causes

A

Vomiting of fluids high in H+ and Cl
Loop diuretics
Mineralcorticoid excess

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3
Q

Large animal causes

A

Sequestration of fluids high in H and CL
Displaced abomasum in ruminants
Displaced stomach
Increased sweating (severe)

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4
Q

Results from

A

A linked loss of H and a retained HCO3

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5
Q

Initiation phase

A

If H and Cl are not getting recycled in the intestines the H is not absorbed and Cl is lost but the carbonic anhydrase is still making bicarb and further decreases the Cl

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6
Q

Electrolyte changes

A

-Cl deficit
-K deficit
-Some Na loss
-Increased HCO3
-Normal anion gap
-Significant water loss
-Decreased effective circulating volume

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7
Q

Maintenance phase

A

Paradoxic aciduria:
Decreased fluid volume due to fluid retention in abomasum-> aldosterone will then be activated and Na is resorbed-> cation secretion (K) and that gets depleted and then H+ gets secreted instead furthering the alkalosis

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8
Q

Compensation

A

-Respiratory response: hypoventilation with increased PCO2

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9
Q

Findings

A

Increased pH
Decreased H
Increased HCO3
Compensatory increased PCO2

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