Metabolic acidosis Flashcards
What can cause excess H production
-Lactic acidosis
-Ketoacidosis
-Ethylene glycol catabolism
-Impaired renal excretion: renal failure, uroperitoneum, distal renal tubular acidosis
Causes of excessive loss of HCO3
-Diarrhea
-Loss of saliva (ruminants)
-Proximal renal tubular acidosis
Titration type
Addition of H+ to blood they are then buffered by HCO3
Secretory type
Loss of HCO3. No increase in anion gap
Distal tubular acidosis
Impaired secretion of H+ in distal tubule
Proximal tubular acidosis
Decreased absorption of HCO3 in the prox. tubule
Consequences of titration type acidosis
Anion gap increases
Compensation for metabolic acidosis
Increased ventilation to reduce pCO2
Characteristics
Decreased pH
Increased H+
Decreased HCO3
Compensation: decreased PCO2