Chronic Renal Disease

Question 1

Decreased renal reserve

Answer 1

Clinically healthy and not polyuric and not azotemic but GFR is about 50%. Don’t recognize clinically

Question 2

Chronic renal insufficiency

Answer 2

Loss of 50-75% of function. Azotemia, anemia, and decrease concentration

Question 3

Chronic renal failure

Answer 3

20-25% function. Azotemia, anemia, decreased concentrating ability, electrolyte imbalance, clinical uremia

Question 4

End stage renal disease

Answer 4

<5% function. Terminal uremia and oliguria or anuria

Question 5

Cause of polyuria in chronic renal disease

Answer 5

1. More solute presented to remaining nephrons (solute diuresis) more water stays in tubules
2. Medullary hypertonicity not maintained
3. Damaged cells less responsive to ADH

Question 6

Species that show hypercalcemia during chronic renal failure

Answer 6

Equines