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Clinical Pathology > Ammonia/Ammonium > Flashcards

Ammonia/Ammonium Flashcards

1
Q

Ammonium

A

NH4+ dominant form in plasma and does not diffuse through membranes

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2
Q

Hyperammonemia

A

-Decreased clearance
-Increased production

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3
Q

Decreased clearance

A

Decreased functional mass of liver
Portosystemic shunt

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4
Q

Increased production

A

Postprandial (transient)
Strenuous exercise (transient)
Bacterial overgrowth

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5
Q

When should you measure blood ammonia

A

-Urea toxicity in cattle
-Hyperammonia in horses without liver disease
-Rare inhereited disorder of urea cycle

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6
Q

Hyperammonemia in horses without liver disease

A

Colic followed by encephalopathic signs due to urease producing bacteria

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7
Q

Samples used for Ammonium measurement

A

EDTA or heparinized

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8
Q

False increases

A

-Hemolysis
-Delayed harvesting of plasma from blood
-Delayed sample analysis

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9
Q

False dicreased

A

-Delayed analysis and exposed to air

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Clinical Pathology (70 decks)

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