Lecture #1 -- Virology Flashcards
True or False. A virus can contain both RNA and DNA.
False. A virus can contain RNA or DNA
How did the International Committee on Taxonomy of Viruses split viruses up?
Order, Family, Subfamily, Genus, Species
How are viruses split up using the Baltimore method?
Families based on type of genetic material (dsDNA, ssDNA, etc.)
Describe the difference between a + and - sense strand.
+ sense strand matches the desired mRNA sequence. - sense strand is complementary.
What are the small types of viral genomes?
RNA ss +/-, RNA ds
What are the larger types of viral genomes?
DNA ss, DNA ds
What are caspids made of?
Viral Proteins
Name two types of caspids. Give an example of each.
Helical (TMV) and Icosahedron (Adenovirus)
What are icosahedrons made of?
Proteins –> Protomers –> Pentomers/Hexomers
Perks of a caspid?
More stable to environmental pressures (acidity, temp, proteases, detergents), increased survival in gut.
Probs for a virus with a caspid?
Virus is more vulnerable to Ab
What do you call a virus without an envelope?
Naked
What is a viral envelope made of?
Lipid, Protein, Glycoproteins
What components of the envelope are viral?
Proteins are viral. Membrane is from the host.
What type of virus will always have an envelope?
Negative strand RNA viruses.
