Herpes Virus - HSV 1 and HSV 2 Flashcards
Genome?
dsDNA
Reservoir?
Humans
Where does the envelope come from?
Nucleus
Alpha-Herpes includes what viruses?
Herpes Simplex 1 and 2
HSV encodes what enzymes?
DNA-dependent DNA pol
Thymidine Kinase
Clinical presentation of HSV?
Usually asymptomatic
Both can cause oral and genital infections
Two types of oral herpes?
Acute Herpetic gingivostomatitis
Cold Sores/Herpes Labialis
Symptoms of Acute Herpetic gingivostomatitis
Clear lesions, then white-ish ulcers
Covers mouth, pharynx
Discomfort, fever, gingivitis, lymphendectomy, difficulty speaking/eating
What age group usually gets Acute Herpetic gingivostomatitis?
Kids 1-4
What herpes usually causes oral herpes?
HSV-1
Describe cold sores.
Vesicles, Ulceration, Inflammation, Edema
What is herpes keratitis? Which virus usually?
Herpes of the eye, HSV-1
Clinical presentation of herpes keratitis?
Unilateral Red Eye, Pain, Photophobia
Dendritic Corneal Ulcer
Most frequent cause of blindness.
What is herpes whitlow?
Herpes of small wounds of hands/wrist through secretions
Clinical presentation of herpes whitlow?
Pain and Burning, Erythema, Edema, Vesicles, Fever