Lec 6 Flashcards
Proteins are made using
Amino acids are joined using covalent peptide bonds to make a polypeptide
This polypeptide can use its primary, secondary, tertiary, or quaternary structure to become part of a protein
Housekeeping genes
Active genes in a cell that are present in different types of cells (ie gut cell and neuron)
Non-cell unique genes
Housekeeping genes make
Glycolysis enzymes
Cell specific genes
Make cells unique
Depictions
Primary structure only
Only shows amino acid not shape
Pancreatic cell takes in pro-insulin and then
Modifies it into insulin and removes it from the cell
Di-sulphide bonds are a part of
Tertiary structure
Space filling
Every atom in a structure is shown
Wire model
Bonds within a structure are shown
Membrane proteins
outside is hydrophilic
Inside is hydrophobic
Phospholipid bilayer
Globular
Compact and soluble
Spends most of its time in water
Hydrophilic amino acid
Ribbon model
Good for showing tertiary structures and secondary structures
What shapes might our proteins come in
Globular
Membrane proteins
Fibrous proteins
Fibrous proteins
Long and thin, bundles into filaments
Regulation of protein synthesis
Most regulation is at the level of RNA synthesis initiation
