lec 37 Flashcards
Plants make toxins to
Kill insect herbivores
Decreasing protein activity is done by a
Protease
Increasing enzyme activity
Activator
Decreasing enzyme activity
Competitive inhibitor
Noncompetitive inhibitor
Increasing receptor activity
Agonist
Decreasing receptor activity
Antagonist
Nicotine
Toxin made by tobacco
Target 1 of nicotine
AChRs (acetylcholine receptor)
Results in euphoria and good feelings in the brain
Target 2 of nicotine
AChRs and adrenal gland cells
Nicotine increases the activity of these receptors
Caffeine target 1
PDE in adrenaline pathway
Caffeine is a competitive inhibitor to PDE
Caffeine target 2
Adenosine
Antagonist to adenosine receptors
Adenosine
Tells the brain that it is tired after it has accumulated throughout the day
Morphine made by
Opium poppies
Target of morphine
Opioid receptors which is meant to Cause euphoria and decrease pain
Morphine adds to this receptor
Heroin
Synthetic derivative of morphine that is dangerous
Codeine
Gets converted to morphine by the liver
slow acting analgesic
Analgesic
Adds to opioid receptor
Fentanyl
Extremely fast acting analgesic
Can be fatal
Naloxone is a
antagonist to morphine
Cannabinoids are found in
Cannabis
Cannabis is grown to either make
Hemp (for clothes)
Marijuana ( for THC which is a drug)
Bill C-45
Cannabis is now legal
Target of Cannabinoids
Cannabinoid receptor
Membrane protein
Is supposed to produce a reward for exercising
Cannabinoid types
THC and CBD
THC
Adds to cannabinoid receptor (strong agonist)
CBD
Weak antagonist to cannabinoid receptor
THC—>CBD leads to
Intoxication
CBD is used for
Health (kinda)
Medical use of cannabinoids
Sativex (1:1 THC to CBD)
Treats multiple sclerosis which attacks myelin
Negative impacts of cannabinoids
Cannabis users have a higher tolerance to sedation
