Lec 20 Flashcards
Intermediate filament
Larger than actin but smaller than microtubules
Intermediate filament structure
Polypeptides come together to make a subunit protein that is a fibrous homodimer
Subunits come together to make intermediate filaments
No + or - end
Assembly and disassembly of intermediate filaments
They are semi-permanent (all or none)
Either subunits or a full intermediate filament
Stability for intermediate filaments is
Desirable
Stability is given by
Cytoskeleton
Nuclear lamina
Formation of extracellular structures
Cytoskeleton
Intermediate filament made with cytokeratin proteins
Nuclear lamina
IFs made with nuclear Lamin proteins that line the inside of the nuclear envelope
Formation of extracellular structures
IFs made with Extracellular keratin proteins from hair, nails etc.